Invitrogen™ Human cIAP2 (aa 311-438) Control Fragment Recombinant Protein

Product Code. 30196371

Brand: Invitrogen™ RP101848

Description

Recombinant Protein

Highest antigen sequence indentity to the following orthologs: Mouse (75%), Rat (75%). This recombinant protein control fragment may be used for blocking experiments with the corresponding antibody, PA5-51700 (PA5-51700. In IHC/ICC and WB experiments, we recommend a 100x molar excess of the protein fragment control based on the concentration and the molecular weight. Pre-incubate the antibody-protein control fragment mixture for 30 min at room temperature.

The protein encoded by this gene is a member of a family of proteins that inhibits apoptosis by binding to tumor necrosis factor receptor-associated factors TRAF1 and TRAF2, probably by interfering with activation of ICE-like proteases. The encoded protein inhibits apoptosis induced by serum deprivation but does not affect apoptosis resulting from exposure to menadione, a potent inducer of free radicals. The amino acid sequence predicts three baculovirus IAP repeat domains and a ring finger domain. Transcript variants encoding the same isoform have been identified.

Specifications

• Accession Number: Q13489
• Concentration: ≥5.0 mg/mL
• For Use With (Application): Blocking Assay, Control
• Formulation: 1 M urea, PBS with no preservative; pH 7.4
• Gene ID (Entrez): 330
• Name: Human cIAP2 (aa 311-438) Control Fragment
• Quantity: 100 μL
• Regulatory Status: RUO
• Gene Alias: AIP 2; AIP1; Api1; Api2; apoptosis inhibitor 1; apoptosis inhibitor 2; AW107670; baculoviral IAP repeat containing 3; baculoviral IAP repeat-containing 2; baculoviral IAP repeat-containing 3; baculoviral IAP repeat-containing protein 3; Birc2; Birc3; Cellular inhibitor of apoptosis 2; cIAP1; cIAP-1; cIAP2; C-IAP2; cIAP-2; H HIAP1; H MALT2; HAIP1; HIAP1; hIAP-1; HIAP2; IAP homolog; IAP homolog C; IAP1; IAP-1; IAP2; Inhibitor of apoptosis protein 1; MALT2; mammalian IAP homolog C; MIAP1; mIAP-1; MIAP2; MIHB; MIHC; RING finger protein 49; RING-type E3 ubiquitin transferase BIRC3; RNF49; TNFR2-TRAF signaling complex protein; TNFR2-TRAF-signaling complex protein 1
• Common Name: cIAP2
• Gene Symbol: BIRC3
• Conjugate: Unconjugated
• Species: Human
• Recombinant: Recombinant
• Protein Tag: His-ABP-tag
• Sequence: QHAKWFPRCEYLIRIKGQEFIRQVQASYPHLLEQLLSTSDSPGDENAESSIIHFEPGEDHSEDAIMMNTPVINAAVEMGFSRSLVKQTVQRKILATGENYRLVNDLVLDLLNAEDEIREEERERATEE
• Content And Storage: -20°C, Avoid Freeze/Thaw Cycles
• Expression System: E. coli
• Form: Liquid
• Purity or Quality Grade: >80% by SDS-PAGE and Coomassie blue staining