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Invitrogen™ Human CHST8 (aa 41-155) Control Fragment Recombinant Protein

Product Code. 30194945
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Quantity:
100 μL
Unit Size:
100µL
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Product Code. 30194945

Brand: Invitrogen™ RP90176

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This item is not returnable. View return policy

Description

Recombinant Protein

Highest antigen sequence indentity to the following orthologs: Mouse (60%), Rat (60%). This recombinant protein control fragment may be used for blocking experiments with the corresponding antibody, PA5-53411 (PA5-53411. In IHC/ICC and WB experiments, we recommend a 100x molar excess of the protein fragment control based on the concentration and the molecular weight. Pre-incubate the antibody-protein control fragment mixture for 30 min at room temperature.

The protein encoded by this gene belongs to the sulfotransferase 2 family. It is predominantly expressed in the pituitary gland, and is localized to the Golgi membrane. This protein catalyzes the transfer of sulfate to position 4 of non-reducing N-acetylgalactosamine (GalNAc) residues in both N-glycans and O-glycans. It is responsible for sulfation of GalNAc on luteinizing hormone (LH), which is required for production of the sex hormones. Mice lacking this enzyme, exhibit increased levels of circulating LH, and precocious sexual maturation of both male and female mice. Alternatively spliced transcript variants have been found for this gene.
TRUSTED_SUSTAINABILITY

Specifications

Accession Number Q9H2A9
Concentration ≥5.0 mg/mL
For Use With (Application) Blocking Assay, Control
Formulation 1 M urea, PBS with no preservative; pH 7.4
Gene ID (Entrez) 64377
Name Human CHST8 (aa 41-155) Control Fragment
Quantity 100 μL
Regulatory Status RUO
Gene Alias 1500011J21Rik; AI426009; carbohydrate (N-acetylgalactosamine 4-0) sulfotransferase 8; carbohydrate N-acetylgalactosamine 4-0 sulfotransferase 8; carbohydrate sulfotransferase 8; Chst8; GalNAc-4-O-sulfotransferase 1; GalNAc4ST; GALNAC4ST1; galNAc-4-ST1; galNAc4ST-1; N-acetylgalactosamine-4-O-sulfotransferase 1; PSS3
Common Name CHST8
Gene Symbol CHST8
Conjugate Unconjugated
Species Human
Recombinant Recombinant
Protein Tag His-ABP-tag
Sequence QVPGIKFNIRPRQPHHDLPPGGSQDGDLKEPTERVTRDLSSGAPRGRNLPAPDQPQPPLQRGTRLRLRQRRRRLLIKKMPAAATIPANSSDAPFIRPGPGTLDGRWVSLHRSQQE
Content And Storage -20°C, Avoid Freeze/Thaw Cycles
Expression System E. coli
Form Liquid
Purity or Quality Grade >80% by SDS-PAGE and Coomassie blue staining
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