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Invitrogen™ Human CHIA (aa 234-305) Control Fragment Recombinant Protein

Product Code. 30196748
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Quantity:
100 μL
Unit Size:
100µL
This item is not returnable. View return policy

Product Code. 30196748

Brand: Invitrogen™ RP94208

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This item is not returnable. View return policy

Recombinant Protein

Highest antigen sequence indentity to the following orthologs: Mouse (82%), Rat (82%). This recombinant protein control fragment may be used for blocking experiments with the corresponding antibody, PA5-63681 (PA5-63681. In IHC/ICC and WB experiments, we recommend a 100x molar excess of the protein fragment control based on the concentration and the molecular weight. Pre-incubate the antibody-protein control fragment mixture for 30 min at room temperature.

CHIA degrades chitin and chitotriose. May participate in the defense against nematodes and other pathogens. There are 3 named isoforms produced by alternative splicing. CHIA is induced via a T helper-2 (Th2)-specific, interleukin-13-mediated pathway in epithelial cells and macrophages. CHIA may be an important mediator of IL13-induced responses in Th2-dominated disorders such as asthma. CHIA hydrolysis N-acetyl-beta-D-glucosaminide 1,4-beta-linkages in chitin and chitodextrins.
TRUSTED_SUSTAINABILITY

Specifications

Accession Number Q9BZP6
Concentration ≥5.0 mg/mL
For Use With (Application) Blocking Assay, Control
Formulation 1 M urea, PBS with no preservative; pH 7.4
Gene ID (Entrez) 27159
Name Human CHIA (aa 234-305) Control Fragment
Quantity 100 μL
Regulatory Status RUO
Gene Alias 2200003E03Rik; acidic chitinase; acidic mammalian chitinase; AMCASE; Chia; Chia1; CHIT2; chitinase, acidic; chitinase, acidic 1; eosinophil chemotactic cytokine; lung-specific protein TSA1902; small acid mammalian chitinase; TSA1902; YNL
Common Name CHIA
Gene Symbol CHIA
Conjugate Unconjugated
Species Human
Recombinant Recombinant
Protein Tag His-ABP-tag
Sequence DTGSNAYLNVDYVMNYWKDNGAPAEKLIVGFPTYGHNFILSNPSNTGIGAPTSGAGPAGPYAKESGIWAYYE
Content And Storage -20°C, Avoid Freeze/Thaw Cycles
Expression System E. coli
Form Liquid
Purity or Quality Grade >80% by SDS-PAGE and Coomassie blue staining
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