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Gibco™ Human Chemerin Recombinant Protein, PeproTech®

Product Code. 17842503
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Quantity:
1 mg
100 μg
25 μg
250 μg
5 μg
500 μg
Unit Size:
100µg
1mg
250µg
25µg
500µg
5µg
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Product Code. 17842503

Brand: Gibco™ 30066100UG

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This item is not returnable. View return policy

Description

Recombinant Protein

Recombinant Human Chemerin is a 15.6 kDa protein consisting of 135 amino acid residues. This product is shipped at ambient temperature. For storage, handling and reconstitution information, please see the lot-specific Certificate of Analysis

Retinoids act through ligand-dependent transcription factors, retinoid X receptor (RXRs) and retinoic acid receptors (RARs). Tazarotene-induced gene (TIG) proteins, also designated retinoic acid receptor responder proteins or RAR-responsive proteins, can be membrane bound or secreted. TIGs act as tumor suppressor genes in human cancers and are highly expressed in skin, hair follicles and endothelial cells as well as in pancreas, spleen and intestine. TIGs are activated by tazarotene and have been implicated as growth regulators that mediate the growth suppressive effects of retinoids. TIG2 is a secreted protein that is mainly expressed in epidermis, hair follicles and endothelial cells. TIG2 is inhibited in psoriatic lesions and is activated by tazarotene in skin rafts and in epidermis of psoriatic lesions.
TRUSTED_SUSTAINABILITY

Specifications

Accession Number Q99969
For Use With (Application) Functional Assay
Formulation protein with no preservative
Gene ID (Entrez) 5919
Molecular Weight (g/mol) 15.6 kDa
Name Human Chemerin
Quantity 100 μg
Source E. coli
Regulatory Status RUO
Endotoxin Concentration <1 EU/ μg
Gene Alias 0610007L05Rik; AI303516; Chemerin; HP10433; Rarres2; RAR-responsive protein TIG2; retinoic acid receptor responder (tazarotene induced) 2; retinoic acid receptor responder 2; retinoic acid receptor responder protein 2; Tazarotene-induced gene 2 protein; TIG2; TIG-2; TIG2HP10433
Common Name Chemerin
Gene Symbol Rarres2
Biological Activity Determined by its ability to chemoattract human immature dendritic cells using a concentration range of 1.0-100.0 ng/ml
Conjugate Unconjugated
Recombinant Recombinant
Sequence ELTEAQRRGL QVALEEFHKH PPVQWAFQET SVESAVDTPF PAGIFVRLEF KLQQTSCRKR DWKKPECKVR PNGRKRKCLA CIKLGSEDKV LGRLVHCPIE TQVLREAEEH QETQCLRVQR AGEDPHSFYF PGQFA
Content And Storage -20°C
Expression System E. coli
Form Lyophilized
Purity or Quality Grade ≥ 98% by SDS-PAGE gel and HPLC analyses.
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