Invitrogen™ Human CES2 (aa 253-332) Control Fragment Recombinant Protein

Product Code. 30194202

Brand: Invitrogen™ RP109883

Description

Recombinant Protein

Highest antigen sequence indentity to the following orthologs: Mouse (75%), Rat (75%). This recombinant protein control fragment may be used for blocking experiments. In IHC/ICC and WB experiments, we recommend a 100x molar excess of the protein fragment control based on the concentration and the molecular weight. Pre-incubate the antibody-protein control fragment mixture for 30 min at room temperature.

CES2 is a member of the carboxylesterase large family. The family members are responsible for the hydrolysis or transesterification of various xenobiotics, such as cocaine and heroin, and endogenous substrates with ester, thioester, or amide bonds. They may participate in fatty acyl and cholesterol ester metabolism, and may play a role in the blood-brain barrier system. The protein encoded by this gene is the major intestinal enzyme and functions in intestine drug clearance.

Specifications

• Accession Number: O00748
• Concentration: ≥5.0 mg/mL
• For Use With (Application): Blocking Assay, Control
• Formulation: 1 M urea, PBS with no preservative; pH 7.4
• Gene ID (Entrez): 8824
• Name: Human CES2 (aa 253-332) Control Fragment
• Quantity: 100 μL
• Regulatory Status: RUO
• Gene Alias: 9030624L02Rik; 9130231C15Rik; ACH M1; Acylcarnitine hydrolase; acylcarnitine hydrolase M1; AI266984; Carboxylesterase 2; carboxylesterase 2 (intestine, liver); carboxylesterase 2 A; carboxylesterase 2 C; carboxylesterase 2 E; carboxylesterase 5; carboxylesterase 6; carboxylesterase isoenzyme; carboxylesterase ML3; CE-2; CES 2; Ces2; CES-2; Ces2a; CES2A1; ces2A3; Ces2c; Ces2e; Ces2l; Ces5; Ces6; CESRL4; Cocaine esterase; hCE-2; ICE; intestinal carboxylesterase; liver carboxylesterase-2; methylumbelliferyl-acetate deacetylase 2; P iCE; PCE-2; Peroxisome proliferator-inducible acylcarnitine hydrolase; phenobarbital-inducible carboxylesterase (liver); pyrethroid hydrolase Ces2a; Pyrethroid hydrolase Ces2e
• Common Name: CES2
• Gene Symbol: CES2
• Conjugate: Unconjugated
• Species: Human
• Recombinant: Recombinant
• Protein Tag: His-ABP-tag
• Sequence: ESGVALLPGLIASSADVISTVVANLSACDQVDSEALVGCLRGKSKEEILAINKPFKMIPGVVDGVFLPRHPQELLASADF
• Content And Storage: -20°C, Avoid Freeze/Thaw Cycles
• Expression System: E. coli
• Form: Liquid
• Purity or Quality Grade: >80% by SDS-PAGE and Coomassie blue staining