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Invitrogen™ Human Cdc42EP5 (aa 118-148) Control Fragment Recombinant Protein

Product Code. 30180739
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Quantity:
100 μL
Unit Size:
100µL
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Product Code. 30180739

Brand: Invitrogen™ RP99145

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This item is not returnable. View return policy

Description

Recombinant Protein

Highest antigen sequence indentity to the following orthologs: Mouse (58%), Rat (58%). This recombinant protein control fragment may be used for blocking experiments with the corresponding antibody, PA5-60367 (PA5-60367. In IHC/ICC and WB experiments, we recommend a 100x molar excess of the protein fragment control based on the concentration and the molecular weight. Pre-incubate the antibody-protein control fragment mixture for 30 min at room temperature.

Cell division control protein 42 (CDC42), a small Rho GTPase, regulates the formation of F-actin-containing structures through its interaction with the downstream effector proteins. The protein encoded by this gene is a member of the Borg (binder of Rho GTPases) family of CDC42 effector proteins. Borg family proteins contain a CRIB (Cdc42/Rac interactive-binding) domain. They bind to CDC42 and regulate its function negatively. The encoded protein may inhibit c-Jun N-terminal kinase (JNK) independently of CDC42 binding. The protein may also play a role in septin organization and inducing pseudopodia formation in fibroblasts [provided by RefSeq, Jul 2013].
TRUSTED_SUSTAINABILITY

Specifications

Accession Number Q6NZY7
Concentration ≥5.0 mg/mL
For Use With (Application) Blocking Assay, Control
Formulation 1 M urea, PBS with no preservative; pH 7.4
Gene ID (Entrez) 148170
Name Human Cdc42EP5 (aa 118-148) Control Fragment
Quantity 100 μL
Regulatory Status RUO
Gene Alias 1700027J19Rik; 2010007O02Rik; binder of Rho GTPase 3; binder of Rho GTPases 3; BORG3; C85526; CDC42 effector protein (Rho GTPase binding) 5; CDC42 effector protein 5; CDC42EP5; Cep5; CRIB-containing BORG3 protein
Common Name CDC42EP5
Gene Symbol CDC42EP5
Conjugate Unconjugated
Species Human
Recombinant Recombinant
Protein Tag His-ABP-tag
Sequence KPDAEPRPGTQPPQARCRPNADLELNDVIGL
Content And Storage -20°C, Avoid Freeze/Thaw Cycles
Expression System E. coli
Form Liquid
Purity or Quality Grade >80% by SDS-PAGE and Coomassie blue staining
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