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Invitrogen™ Human Cdc42EP3 (aa 108-172) Control Fragment Recombinant Protein

Product Code. 30196135
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Quantity:
100 μL
Unit Size:
100µL
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Product Code. 30196135

Brand: Invitrogen™ RP96179

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Description

Recombinant Protein

Highest antigen sequence indentity to the following orthologs: Mouse (91%), Rat (91%). This recombinant protein control fragment may be used for blocking experiments with the corresponding antibody, PA5-57102 (PA5-57102. In IHC/ICC and WB experiments, we recommend a 100x molar excess of the protein fragment control based on the concentration and the molecular weight. Pre-incubate the antibody-protein control fragment mixture for 30 min at room temperature.

CDC42, a small Rho GTPase, regulates the formation of F-actin-containing structures through its interaction with the downstream effector proteins. The protein encoded by this gene is a member of the Borg family of CDC42 effector proteins. Borg family proteins contain a CRIB (Cdc42/Rac interactive-binding) domain. They bind to, and negatively regulate the function of, CDC42. This protein can interact with CDC42, as well as with the ras homolog gene family, member Q (ARHQ/TC10). Expression of this protein in fibroblasts has been shown to induce pseudopodia formation.
TRUSTED_SUSTAINABILITY

Specifications

Accession Number Q9UKI2
Concentration ≥5.0 mg/mL
For Use With (Application) Blocking Assay, Control
Formulation 1 M urea, PBS with no preservative; pH 7.4
Gene ID (Entrez) 10602
Name Human Cdc42EP3 (aa 108-172) Control Fragment
Quantity 100 μL
Regulatory Status RUO
Gene Alias 3200001F04Rik; AA986861; Binder of Rho GTPases 2; BORG2; CDC42 effector protein (Rho GTPase binding) 3; CDC42 effector protein 3; Cdc42ep3; CEP3; CRIB-containing BORG2 protein; MSE55-related Cdc42-binding protein; MSE55-related protein; UB1
Common Name CDC42EP3
Gene Symbol CDC42EP3
Conjugate Unconjugated
Species Human
Recombinant Recombinant
Protein Tag His-ABP-tag
Sequence SLPTIGGSQALMLPLLSPVTFNSKQESFGPAKLPRLSCEPVMEEKAQEKSSLLENGTVHQGDTSW
Content And Storage -20°C, Avoid Freeze/Thaw Cycles
Expression System E. coli
Form Liquid
Purity or Quality Grade >80% by SDS-PAGE and Coomassie blue staining
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