Invitrogen™ Human CD264 (TRAIL-R4) (aa 331-362) Control Fragment Recombinant Protein

Product Code. 30208719

Brand: Invitrogen™ RP107784

Description

Recombinant Protein

Highest antigen sequence indentity to the following orthologs: Mouse (41%), Rat (41%). This recombinant protein control fragment may be used for blocking experiments with the corresponding antibody, PA5-84853 (PA5-84853. In IHC/ICC and WB experiments, we recommend a 100x molar excess of the protein fragment control based on the concentration and the molecular weight. Pre-incubate the antibody-protein control fragment mixture for 30 min at room temperature.

TRAIL (also known as Apo-2L) is a member of the tumor necrosis factor (TNF) ligand family that rapidly induces apoptosis in a variety of transformed cell lines. A fourth member of the emerging TRAIL receptor family, TRAIL-R4, has signaling capacity similar to that of TRAIL-R1 and TRAIL-R2 with respect to NF-kappaB activation, but differs in its inability to induce apoptosis. Like TRAIL-R1 and TRAIL-R2, this receptor shows widespread tissue expression. The human TRAIL-R4 gene has been mapped to chromosome 8p22-21, clustered with three other TRAIL receptors.

Specifications

• Accession Number: Q9UBN6
• Concentration: ≥5.0 mg/mL
• For Use With (Application): Blocking Assay, Control
• Formulation: 1 M urea, PBS with no preservative; pH 7.4
• Gene ID (Entrez): 8793
• Name: Human CD264 (TRAIL-R4) (aa 331-362) Control Fragment
• Quantity: 100 μL
• Regulatory Status: RUO
• Gene Alias: CD264; DCR2; Decoy receptor 2; TNF receptor superfamily member 10 d; TNF receptor-related receptor for TRAIL; TNF-related apoptosis-inducing ligand receptor 4; TNFRSF10D; TRAIL receptor 4; TRAIL receptor with a truncated death domain; TRAILR4; TRAIL-R4; TRUNDD; Tumor necrosis factor receptor superfamily member 10 D; tumor necrosis factor receptor superfamily member 10 d, decoy with truncated death domain; tumor necrosis factor receptor superfamily, member 10 d, decoy with truncated death domain; UNQ251/PRO288
• Common Name: TRAIL-R4 (CD264)
• Gene Symbol: TNFRSF10D
• Conjugate: Unconjugated
• Species: Human
• Recombinant: Recombinant
• Protein Tag: His-ABP-tag
• Sequence: LLVPVNDADSADISTLLDASATLEEGHAKETI
• Content And Storage: -20°C, Avoid Freeze/Thaw Cycles
• Expression System: E. coli
• Form: Liquid
• Purity or Quality Grade: >80% by SDS-PAGE and Coomassie blue staining