Gibco™ Human CCL25 (TECK) Recombinant Protein, PeproTech®

Product Code. 17882553

Brand: Gibco™ 30045500UG

Description

Recombinant Protein

Recombinant Human TECK is a 14.2 kDa protein containing 127 amino acid residues, including the four conserved cysteine residues present in CC chemokines. This product is shipped at ambient temperature. For storage, handling and reconstitution information, please see the lot-specific Certificate of Analysis

Chemokines are likely to play an important role in regulating the trafficking of developing T cells within the thymus. Chemokine C-C thymus expressed chemokine (TECK), also designated chemokine ligand 25 (CCL25), small induc-ible cytokine A25, chemokine b-15 or CK b-15, is expressed predominantly in thymic dendritic cells, thymic epithelial cells and in the small intestine. TECK, a CCR9 ligand, has suppressive activity against immature subsets of myeloid progenitors which have been stimulated to proliferate by multiple growth factors. TECK delivers signals through CCR9, which is important for the nav-igation of developing thymocytes. Bone marrow pre-pro-B cells and cells capable of generating pro-B colonies in the presence of interleukin-7 and Flt-3 ligand migrate to TECK, a response lost in later stages of B cell development.

Specifications

• Accession Number: O15444
• For Use With (Application): Control, Western Blot Control, ELISA Standard, Binding Assay, Bioactivity
• Formulation: Protein with no preservative
• Gene ID (Entrez): 6370
• Molecular Weight (g/mol): 14.2 kDa
• Name: Human CCL25 (TECK)
• Purification Method: Purified
• Quantity: 500 μg
• Source: E. coli
• Storage Requirements: -20°C
• Regulatory Status: RUO
• Endotoxin Concentration: <1 EU/μg
• Gene Alias: A130072A22Rik; AI852536; C-C motif chemokine 25; C-C motif chemokine ligand 25; CCL25; chemokine (C-C motif) ligand 25; chemokine TECK; Ck beta-15; CKb15; Scya25; SCYA25TECKvar; small inducible chemokine 25; small inducible cytokine A25; small inducible cytokine subfamily A (Cys-Cys), member 25; small-inducible cytokine A25; Teck; TECKMGC150327; TECKvar; thymus expressed chemokine; thymus-expressed chemokine
• Common Name: TECK
• Gene Symbol: CCL25
• Biological Activity: Determined by its ability to bind CCR9 receptor expressed on the surface of MOLT4 cells.
• Product Type: Protein
• Conjugate: Unconjugated
• Recombinant: Recombinant
• Sequence: QGVFEDCCLA YHYPIGWAVL RRAWTYRIQE VSGSCNLPAA IFYLPKRHRK VCGNPKSREV QRAMKLLDAR NKVFAKLHHN MQTFQAGPHA VKKLSSGNSK LSSSKFSNPI SSSKRNVSLL ISANSGL
• Content And Storage: -20°C
• Activity: Determined by its ability to bind CCR9 receptor expressed on the surface of MOLT4 cells.
• Expression System: E. coli
• Form: Lyophilized
• Purity or Quality Grade: ≥ 98% by SDS-PAGE gel and HPLC analyses.