Invitrogen™ Human CCDC22 (aa 284-377) Control Fragment Recombinant Protein

Product Code. 30208140

Brand: Invitrogen™ RP110092

Description

Recombinant Protein

Highest antigen sequence indentity to the following orthologs: Mouse (78%), Rat (78%). This recombinant protein control fragment may be used for blocking experiments with the corresponding antibody, PA5-145123 (PA5-145123. In IHC/ICC and WB experiments, we recommend a 100x molar excess of the protein fragment control based on the concentration and the molecular weight. Pre-incubate the antibody-protein control fragment mixture for 30 min at room temperature.

CCDC22 is a recently identified coiled-coil domain-containing protein that has been shown to bind copines, which are calcium-dependent, membrane-binding proteins that may function in calcium signaling. In rat, CCDC22 has been observed to localize in multiple regions of the brain, including the prefrontal and somatosensory cortex, dentate gyrus and thalamus, and in the ipsilateral motor neurons of the spinal cord after sciatic nerve transection suggesting that it may play a role in neuronal injury response. The human CCDC22 gene has been identified as a novel candidate gene for syndromic X-linked intellectual disability (XLID).

Specifications

• Accession Number: O60826
• Concentration: ≥5.0 mg/mL
• For Use With (Application): Blocking Assay, Control
• Formulation: 1 M urea, PBS with no preservative; pH 7.4
• Gene ID (Entrez): 28952
• Name: Human CCDC22 (aa 284-377) Control Fragment
• Quantity: 100 μL
• Regulatory Status: RUO
• Gene Alias: AI481216; Ccdc22; ccdc22 {ECO:0000250; coiled-coil domain containing 22; coiled-coil domain-containing protein 22; coiled-coil domain-containing protein 22 {ECO:0000250; CXorf37; DXImx40e; JM1; Ppp1r3f; RGD1560910; RTSC2; Sfc22; UniProtKB:O60826}
• Common Name: CCDC22
• Gene Symbol: Ccdc22
• Conjugate: Unconjugated
• Species: Human
• Recombinant: Recombinant
• Protein Tag: His-ABP-tag
• Sequence: KTGAPKGSRFTHSEKFTFHLEPQAQATQVSDVPATSRRPEQVTWAAQEQELESLREQLEGVNRSIEEVEADMKTLGVSFVQAESECRHSKLSTA
• Content And Storage: -20°C, Avoid Freeze/Thaw Cycles
• Expression System: E. coli
• Form: Liquid
• Purity or Quality Grade: >80% by SDS-PAGE and Coomassie blue staining