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Invitrogen™ Human CCDC134 (aa 170-202) Control Fragment Recombinant Protein

Product Code. 30211919
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Quantity:
100 μL
Unit Size:
100µL
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Product Code. 30211919

Brand: Invitrogen™ RP110232

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This item is not returnable. View return policy

Description

Recombinant Protein

Highest antigen sequence indentity to the following orthologs: Mouse (85%), Rat (85%). This recombinant protein control fragment may be used for blocking experiments with the corresponding antibody, PA5-145105 (PA5-145105. In IHC/ICC and WB experiments, we recommend a 100x molar excess of the protein fragment control based on the concentration and the molecular weight. Pre-incubate the antibody-protein control fragment mixture for 30 min at room temperature.

The coiled-coil domain is a common protein motif that is often involved in protein oligomerization and is found in proteins such as transcription factors and intermediate filaments. One such protein is CCDC134, a recently identified secretory protein that has been found to inhibit the transcriptional activity of the Elk1 protein. Overexpression CCDC134 also inhibited the phosphorylation of Erk and JNK/SAPK but not p38 MAPK, while specific siRNA against CCDC134 activated Elk1 transcriptional activity and the phosphorylation of Erk and JNK/SAPK, suggesting a potential inhibiting role of CCDC134 in MAPK-mediated Elk1 transcription. CCDC134 is widely expressing in normal adult tissues, tumors, and cell lines.
TRUSTED_SUSTAINABILITY

Specifications

Accession Number Q9H6E4
Concentration ≥5.0 mg/mL
For Use With (Application) Blocking Assay, Control
Formulation 1 M urea, PBS with no preservative; pH 7.4
Gene ID (Entrez) 79879
Name Human CCDC134 (aa 170-202) Control Fragment
Quantity 100 μL
Regulatory Status RUO
Gene Alias 2310042L06Rik; AW208859; Ccdc134; coiled-coil domain containing 134; coiled-coil domain-containing protein 134; dJ821D11.3
Common Name CCDC134
Gene Symbol CCDC134
Conjugate Unconjugated
Species Human
Recombinant Recombinant
Protein Tag His-ABP-tag
Sequence GISEKDSNFQNPFKIDRTEFIPSTDPFQKALRE
Content And Storage -20°C, Avoid Freeze/Thaw Cycles
Expression System E. coli
Form Liquid
Purity or Quality Grade >80% by SDS-PAGE and Coomassie blue staining
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