Invitrogen™ Human CALHM2 (aa 124-185) Control Fragment Recombinant Protein

Product Code. 30196880

Brand: Invitrogen™ RP91152

Description

Recombinant Protein

Highest antigen sequence indentity to the following orthologs: Mouse (82%), Rat (82%). This recombinant protein control fragment may be used for blocking experiments with the corresponding antibody, PA5-53219 (PA5-53219. In IHC/ICC and WB experiments, we recommend a 100x molar excess of the protein fragment control based on the concentration and the molecular weight. Pre-incubate the antibody-protein control fragment mixture for 30 min at room temperature.

CALHM2, also named as FAM26B, is a pore-forming subunit of a voltage-gated ion channel. It is a critical ATP-releasing channel that modulates neural activity and as a potential risk factor of depression. There are three isoforms of CALHM2 with calculated MW 36 kDa, 24 kDa and 22 kDa. It is about 32-36 kDa in western blot with membrane protein extracted lysate.

Specifications

• Accession Number: Q9HA72
• Concentration: ≥5.0 mg/mL
• For Use With (Application): Blocking Assay, Control
• Formulation: 1 M urea, PBS with no preservative; pH 7.4
• Gene ID (Entrez): 51063
• Name: Human CALHM2 (aa 124-185) Control Fragment
• Quantity: 100 μL
• Regulatory Status: RUO
• Gene Alias: 2810048G17Rik; calcium homeostasis modulator 2; calcium homeostasis modulator protein 2; CALHM2; Fam26b; family with sequence similarity 26, member B; Protein FAM26B; RGD1308276
• Common Name: CALHM2
• Gene Symbol: Calhm2
• Conjugate: Unconjugated
• Species: Human
• Recombinant: Recombinant
• Protein Tag: His-ABP-tag
• Sequence: RGEAYVCALSEFVDPSSLTAREEHFPSAHATEILARFPCKENPDNLSDFREEVSRRLRYESQ
• Content And Storage: -20°C, Avoid Freeze/Thaw Cycles
• Expression System: E. coli
• Form: Liquid
• Purity or Quality Grade: >80% by SDS-PAGE and Coomassie blue staining