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Invitrogen™ Human C1orf86 (aa 108-180) Control Fragment Recombinant Protein
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Quantity:
100 μL
Unit Size:
100µL
Description
Highest antigen sequence indentity to the following orthologs: Mouse (58%), Rat (58%). This recombinant protein control fragment may be used for blocking experiments with the corresponding antibody, PA5-58555 (PA5-58555. In IHC/ICC and WB experiments, we recommend a 100x molar excess of the protein fragment control based on the concentration and the molecular weight. Pre-incubate the antibody-protein control fragment mixture for 30 min at room temperature.
C1orf86 is a component of the Fanconi anemia (FA) complex required to recruit the FA complex to DNA interstrand cross-links (ICLs) and promote ICLs repair. Following DNA damage recognizes and binds 'Lys-63'-linked ubiquitin generated by RNF8 at ICLs and recruits other components of the FA complex. It promotes translesion synthesis via interaction with REV1.
Specifications
Specifications
| Accession Number | Q6NZ36 |
| Concentration | ≥5.0 mg/mL |
| For Use With (Application) | Blocking Assay, Control |
| Formulation | 1 M urea, PBS with no preservative; pH 7.4 |
| Gene ID (Entrez) | 199990 |
| Name | Human C1orf86 (aa 108-180) Control Fragment |
| Quantity | 100 μL |
| Regulatory Status | RUO |
| Gene Alias | 2610002J02Rik; C1orf86; Faap20; FANCA-associated protein of 20 kDa; Fanconi anemia core complex associated protein 20; Fanconi anemia core complex-associated protein 20; Fanconi anemia-associated protein of 20 kDa; FP7162; likely orthologue of H. sapiens chromosome 1 open reading frame 86 (C1orf86); LOC362678; RGD1308923; RIKEN cDNA 2610002J02 gene |
| Common Name | C1orf86 |
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