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Invitrogen™ Human C17orf71 (aa 322-454) Control Fragment Recombinant Protein

Product Code. 30200801
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Quantity:
100 μL
Unit Size:
100µL
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Product Code. 30200801

Brand: Invitrogen™ RP93372

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This item is not returnable. View return policy

Description

Recombinant Protein

Highest antigen sequence indentity to the following orthologs: Mouse (97%), Rat (97%). This recombinant protein control fragment may be used for blocking experiments with the corresponding antibody, PA5-55202 (PA5-55202. In IHC/ICC and WB experiments, we recommend a 100x molar excess of the protein fragment control based on the concentration and the molecular weight. Pre-incubate the antibody-protein control fragment mixture for 30 min at room temperature.

Involved in nonsense-mediated decay (NMD) of mRNAs containing premature stop codons. Is recruited by release factors to stalled ribosomes together with SMG1 and SMG9 (forming the SMG1C protein kinase complex) and, in the SMG1C complex, is required to mediate the recruitment of SMG1 to the ribosome:SURF complex and to suppress SMG1 kinase activity until the ribosome:SURF complex locates the exon junction complex (EJC). Acts as a regulator of kinase activity. [UniProt]
TRUSTED_SUSTAINABILITY

Specifications

Accession Number Q8ND04
Concentration ≥5.0 mg/mL
For Use With (Application) Blocking Assay, Control
Formulation 1 M urea, PBS with no preservative; pH 7.4
Gene ID (Entrez) 55181
Name Human C17orf71 (aa 322-454) Control Fragment
Quantity 100 μL
Regulatory Status RUO
Gene Alias 1200011M11Rik; ABC2; Amplified in breast cancer gene 2 protein; C17orf71; C19H17orf71; CG6729 gene product; FLJ10587; FLJ23205; Protein SMG8; protein smg-8 homolog; RGD1306862; Smg8; smg-8 homolog, nonsense mediated mRNA decay factor; smg-8 homolog, nonsense mediated mRNA decay factor (C. elegans); SMG8 nonsense mediated mRNA decay factor; SMG8, nonsense mediated mRNA decay factor
Common Name C17orf71
Gene Symbol SMG8
Conjugate Unconjugated
Species Human
Recombinant Recombinant
Protein Tag His-ABP-tag
Sequence SINCLFTVPANQAFVYIVPGSQEEDPVGMLLDQLRSHCTVKDPESLLVPAPLSGPRRYQVMRQHSRQQLSFHIDSSSSSSSGQLVDFTLREFLWQHVELVLSKKGFDDSVGRNPQPSHFELPTYQKWISAASK
Content And Storage -20°C, Avoid Freeze/Thaw Cycles
Expression System E. coli
Form Liquid
Purity or Quality Grade >80% by SDS-PAGE and Coomassie blue staining
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