Invitrogen™ Human C/EBP zeta (aa 359-459) Control Fragment Recombinant Protein

Product Code. 30210359

Brand: Invitrogen™ RP91656

Description

Recombinant Protein

Highest antigen sequence indentity to the following orthologs: Mouse (89%), Rat (89%). This recombinant protein control fragment may be used for blocking experiments with the corresponding antibody, PA5-84099 (PA5-84099. In IHC/ICC and WB experiments, we recommend a 100x molar excess of the protein fragment control based on the concentration and the molecular weight. Pre-incubate the antibody-protein control fragment mixture for 30 min at room temperature.

This gene belongs to the CEBP family. The encoded protein plays a role in cellular response to environmental stimuli through a transcriptional process that involves heat shock factors, conserved DNA elements (heat shock elements or HSEs) and CCAAT boxes. The protein acts as a DNA-binding transcriptional activator and regulates the heat-shock protein 70 (HSP70) promoter in a CCAAT-dependent manner. The protein is also involved in cell growth and differentiation, particularly, hematopoietic differentiation. Methylation of the promoter of this gene or mutations within the gene may be correlated with occurrence of acute myeloid leukemia (AML).

Specifications

• Accession Number: Q03701
• Concentration: ≥5.0 mg/mL
• For Use With (Application): Blocking Assay, Control
• Formulation: 1 M urea, PBS with no preservative; pH 7.4
• Gene ID (Entrez): 10153
• Name: Human C/EBP zeta (aa 359-459) Control Fragment
• Quantity: 100 μL
• Regulatory Status: RUO
• Gene Alias: AI848081; C EBP; C/EBP zeta; CBF; Cbf2; CCAAT/enhancer binding protein (C/EBP), zeta; CCAAT/enhancer binding protein alpha (C/EBP) related sequence 1; CCAAT/enhancer binding protein cebp family zeta; CCAAT/enhancer binding protein zeta; CCAAT/enhancer-binding protein zeta; CCAAT-binding factor; CCAAT-box-binding transcription factor; CEBP zeta; Cebpa-rs1; CEBPZ; core-binding factor; CTF2; HSPCBF; HSP-CBF; NOC1
• Common Name: C/EBP zeta
• Gene Symbol: CEBPZ
• Conjugate: Unconjugated
• Species: Human
• Recombinant: Recombinant
• Protein Tag: His-ABP-tag
• Sequence: VTTKTRALTVAHELLCNKPEEEKALLVQVVNKLGDPQNRIATKASHLLETLLCKHPNMKGVVSGEVERLLFRSNISSKAQYYAICFLNQMALSHEESELAN
• Content And Storage: -20°C, Avoid Freeze/Thaw Cycles
• Expression System: E. coli
• Form: Liquid
• Purity or Quality Grade: >80% by SDS-PAGE and Coomassie blue staining