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Invitrogen™ Human BACE2 (aa 503-518) Synthetic Peptide
Description
Human BACE2 (residues 503-518) Synthetic Peptide, PEP-167, from Invitrogen.
BACE2 or Beta Secretase 2 is responsible for the proteolytic processing of the amyloid precursor protein (APP). BACE2 cleaves APP between residues 690 and 691. This cleavage leads to the generation and extracellular release of beta-cleaved soluble APP. BACE2 is also know to cleave APP between residues 671 and 672. Accumulation of APP is a signature of Alzheimer disease and frequent complication of adult Down syndrome patients.
Specifications
Specifications
| Gene ID (Entrez) | 25825 |
| Species | Human |
| Purification Method | purified |
| Accession Number | Q9Y5Z0 |
| Common Name | Human BACE2 (aa 503-518) |
| Concentration | 0.5 mg/mL |
| Content And Storage | -20°C. Avoid freeze-thaw cycles. |
| Description | Synthetic Peptide |
| Format | Lyophilized |
| Formulation | peptide with no preservative |
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