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Invitrogen™ Human Artemin ELISA Kit

Product Code. 17135159
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Product Code. 17135159 Supplier Invitrogen™ Supplier No. EH37RBX5

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ELISA

Human Artemin quantitates human Artemin in serum, plasma, supernatant. The assay will exclusively recognize both natural and recombinant human Artemin.

The protein encoded by this gene is a member of the glial cell line-derived neurotophic factor (GDNF) family of ligands which are a group of ligands within the TGF-beta superfamily of signaling molecules. GDNFs are unique in having neurotrophic properties and have potential use for gene therapy in neurodegenerative disease. Artemin has been shown in culture to support the survival of a number of peripheral neuron populations and at least one population of dopaminergic CNS neurons. Its role in the PNS and CNS is further substantiated by its expression pattern in the proximity of these neurons. This protein is a ligand for the RET receptor and uses GFR-alpha 3 as a coreceptor. Multiple transcript variants encoding different isoforms have been found for this gene.
TRUSTED_SUSTAINABILITY

Specifications

Accession Number Artemin; ARTN; Enovin; EVN; NBN; neublastin; neurotrophic factor
Assay Range 4.10 to 1,000 pg/mL
Assay Sensitivity 4 pg/mL
Conjugate HRP
Product Type ELISA
Sample Type Plasma, Serum, Supernatant
For Use With (Equipment) Colorimetric Microplate Reader
Gene ID (Entrez) 9048
Gene Symbol ARTN
Interassay CV <12%
Intraassay CV <10
Kit Contents Pre-coated 96 well plate, Standard, Assay Diluent concentrate, Biotinylated Detection Antibody, SAV-HRP, Wash Buffer, Chromogen, Stop Solution, Adhesive Plate Covers
Label or Dye HRP
Quantity 5 x 96 Tests
Regulatory Status RUO
Sample Volume Plasma 50 μL, Serum 50 μL, Supernatant 50 μL
Storage Requirements 2°C to 8°C
Target Artemin
Test Time 1 hrs 20 mins
Total Assay Time 4 hrs 45 mins
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