Invitrogen™ Human ARHGEF10 (aa 194-291) Control Fragment Recombinant Protein

Product Code. 30194722

Brand: Invitrogen™ RP93758

Description

Recombinant Protein

Highest antigen sequence indentity to the following orthologs: Mouse (86%), Rat (86%). This recombinant protein control fragment may be used for blocking experiments with the corresponding antibody, PA5-55139 (PA5-55139. In IHC/ICC and WB experiments, we recommend a 100x molar excess of the protein fragment control based on the concentration and the molecular weight. Pre-incubate the antibody-protein control fragment mixture for 30 min at room temperature.

This gene encodes a Rho guanine nucleotide exchange factor (GEF). Rho GEFs regulate the activity of small Rho GTPases by stimulating the exchange of guanine diphosphate (GDP) for guanine triphosphate (GTP) and may play a role in neural morphogenesis. Mutations in this gene are associated with slowed nerve conduction velocity (SNCV). Alternative splicing results in multiple transcript variants.

Specifications

• Accession Number: O15013
• Concentration: ≥5.0 mg/mL
• For Use With (Application): Blocking Assay, Control
• Formulation: 1 M urea, PBS with no preservative; pH 7.4
• Gene ID (Entrez): 9639
• Name: Human ARHGEF10 (aa 194-291) Control Fragment
• Quantity: 100 μL
• Regulatory Status: RUO
• Gene Alias: 6430549H08Rik; Arhgef10; GEF10; Kiaa0294; mKIAA0294; RGD1565043; Rho guanine nucleotide exchange factor (GEF) 10; Rho guanine nucleotide exchange factor 10; SNCV
• Common Name: ARHGEF10
• Gene Symbol: ARHGEF10
• Conjugate: Unconjugated
• Species: Human
• Recombinant: Recombinant
• Protein Tag: His-ABP-tag
• Sequence: RQPNSLSSEEPPTSEDQVGREDSALARWAADPANTAWMENPEEAIYDDVPRENSDSEPDEMIYDDVENGDEGGNSSLEYGWSSSEFESYEEQSDSECK
• Content And Storage: -20°C, Avoid Freeze/Thaw Cycles
• Expression System: E. coli
• Form: Liquid
• Purity or Quality Grade: >80% by SDS-PAGE and Coomassie blue staining