Invitrogen™ Human APOBEC3B (aa 255-279) Control Fragment Recombinant Protein

Product Code. 30211339

Brand: Invitrogen™ RP105404

Description

Recombinant Protein

Highest antigen sequence indentity to the following orthologs: Mouse (52%), Rat (52%). This recombinant protein control fragment may be used for blocking experiments with the corresponding antibody, PA5-66863 (PA5-66863. In IHC/ICC and WB experiments, we recommend a 100x molar excess of the protein fragment control based on the concentration and the molecular weight. Pre-incubate the antibody-protein control fragment mixture for 30 min at room temperature.

This gene is a member of the cytidine deaminase gene family. It is one of seven related genes or pseudogenes found in a cluster, thought to result from gene duplication, on chromosome 22. Members of the cluster encode proteins that are structurally and functionally related to the C to U RNA-editing cytidine deaminase APOBEC1. It is thought that the proteins may be RNA editing enzymes and have roles in growth or cell cycle control. A hybrid gene results from the deletion of approximately 29.5 kb of sequence between this gene, APOBEC3B, and the adjacent gene APOBEC3A. The breakpoints of the deletion are within the two genes, so the deletion allele is predicted to have the promoter and coding region of APOBEC3A, but the 3' UTR of APOBEC3B. Two transcript variants encoding different isoforms have been found for this gene.

Specifications

• Accession Number: Q9UH17
• Concentration: ≥5.0 mg/mL
• For Use With (Application): Blocking Assay, Control
• Formulation: 1 M urea, PBS with no preservative; pH 7.4
• Gene ID (Entrez): 9582
• Name: Human APOBEC3B (aa 255-279) Control Fragment
• Quantity: 100 μL
• Regulatory Status: RUO
• Gene Alias: A3B; A3Z2_1; A3Z2-Z3; A3Z3; A3Z3_1; APOBEC1L; Apobec3; Apobec3b; Apobec3f; APOBEC3F1; APOBEC3F2; APOBEC3Z2; APOBEC3Z3; apolipoprotein B editing complex 3; apolipoprotein B mRNA editing enzyme catalytic polypeptide like 3 B; apolipoprotein B mRNA editing enzyme catalytic polypeptide-like 3 B; apolipoprotein B mRNA editing enzyme catalytic subunit 3 B; apolipoprotein B mRNA editing enzyme, catalytic polypeptide 3; apolipoprotein B mRNA editing enzyme, catalytic polypeptide-like 3 B; apolipoprotein B mRNA editing enzyme, catalytic polypeptide-like 3 F; apolipoprotein B mRNA-editing complex 3; ARCD3; Arp3; ARP4; BC003314; bK150C 2.2; bK150C2.2; Cem15; CEM-15; cytidine deaminase; DJ742C19.2; DNA dC->dU-editing enzyme APOBEC3; DNA dC->dU-editing enzyme APOBEC-3; DNA dC->dU-editing enzyme APOBEC-3 B; FLJ21201; phorbolin 2; phorbolin 3; phorbolin-1-related protein; Phorbolin-2/3; PHRBNL; probable DNA dC->dU-editing enzyme APOBEC3; probable DNA dC->dU-editing enzyme APOBEC-3 B; recovery from Friend virus 3; Rfv3
• Common Name: APOBEC3B
• Gene Symbol: APOBEC3B
• Conjugate: Unconjugated
• Species: Human
• Recombinant: Recombinant
• Protein Tag: His-ABP-tag
• Sequence: ELRFLDLVPSLQLDPAQIYRVTWFI
• Content And Storage: -20°C, Avoid Freeze/Thaw Cycles
• Expression System: E. coli
• Form: Liquid
• Purity or Quality Grade: >80% by SDS-PAGE and Coomassie blue staining