Invitrogen™ Human AP2 alpha (aa 98-123) Control Fragment Recombinant Protein

Product Code. 30204123

Brand: Invitrogen™ RP103276

Description

Recombinant Protein

Highest antigen sequence indentity to the following orthologs: Mouse (100%), Rat (100%). This recombinant protein control fragment may be used for blocking experiments with the corresponding antibody, PA5-84317 (PA5-84317. In IHC/ICC and WB experiments, we recommend a 100x molar excess of the protein fragment control based on the concentration and the molecular weight. Pre-incubate the antibody-protein control fragment mixture for 30 min at room temperature.

TFAP2A is a sequence-specific DNA-binding protein that interacts with inducible viral and cellular enhancer elements to regulate transcription of selected genes. AP-2 factors bind to the consensus sequence 5'-GCCNNNGGC-3' and activate genes involved in a large spectrum of important biological functions including proper eye, face, body wall, limbs and neural tube development. They also suppress a number of genes including MCAM/MUC18, C/EBP alpha and MYC. TFAP2A is the only AP-2 protein required for early morphogenesis of the lens vesicle.

Specifications

• Accession Number: P05549
• Concentration: ≥5.0 mg/mL
• For Use With (Application): Blocking Assay, Control
• Formulation: 1 M urea, PBS with no preservative; pH 7.4
• Gene ID (Entrez): 7020
• Name: Human AP2 alpha (aa 98-123) Control Fragment
• Quantity: 100 μL
• Regulatory Status: RUO
• Gene Alias: activating enhancer-binding protein 2 alpha; activating enhancer-binding protein 2-alpha; Activator protein 2; activator protein 2 alpha variant 4; activator protein 2 alpha variant 6; activator protein 2 alpha variant 7; AP2; AP-2; Ap-2 (a); AP-2 transcription factor; AP2alpha; AP-2 alpha; AP2-alpha; Ap2tf; BOFS; ERF-1; FLJ51761; OTTHUMP00000214240; OTTHUMP00000214243; Tcfap2a; TFAP2; TFAP2A; transcription factor AP2; transcription factor AP-2 alpha; transcription factor AP-2 alpha (activating enhancer binding protein 2 alpha); transcription factor AP-2, alpha; transcription factor AP-2-alpha; transcription factor AP-2-alpha-like; transcription factor; AP-2
• Common Name: AP2 alpha
• Gene Symbol: TFAP2A
• Conjugate: Unconjugated
• Species: Human
• Recombinant: Recombinant
• Protein Tag: His-ABP-tag
• Sequence: GQRQSQESGLLHTHRGLPHQLSGLDP
• Content And Storage: -20°C, Avoid Freeze/Thaw Cycles
• Expression System: E. coli
• Form: Liquid
• Purity or Quality Grade: >80% by SDS-PAGE and Coomassie blue staining