Invitrogen™ Human ANKH (aa 448-492) Control Fragment Recombinant Protein

Product Code. 30210812

Brand: Invitrogen™ RP107620

Description

Recombinant Protein

Highest antigen sequence indentity to the following orthologs: Mouse (100%), Rat (100%). This recombinant protein control fragment may be used for blocking experiments with the corresponding antibody, PA5-66977 (PA5-66977. In IHC/ICC and WB experiments, we recommend a 100x molar excess of the protein fragment control based on the concentration and the molecular weight. Pre-incubate the antibody-protein control fragment mixture for 30 min at room temperature.

ANKH is a multipass transmembrane protein that is expressed in joints and other tissues and controls pyrophosphate levels in cultured cells. Progressive ankylosis-mediated control of pyrophosphate levels has been suggested as a possible mechanism regulating tissue calcification and susceptibility to arthritis in higher animals.

Specifications

• Accession Number: Q9HCJ1
• Concentration: ≥5.0 mg/mL
• For Use With (Application): Blocking Assay, Control
• Formulation: 1 M urea, PBS with no preservative; pH 7.4
• Gene ID (Entrez): 56172
• Name: Human ANKH (aa 448-492) Control Fragment
• Quantity: 100 μL
• Regulatory Status: RUO
• Gene Alias: Ank; ANKH; ANKH inorganic pyrophosphate transport regulator; ankylosis, progressive homolog; CCAL2; CMDJ; CPPDD; D15Ertd221e; FLJ27166; fn54 protein; HANK; KIAA1581; MANK; mKIAA1581; progessive ankylosis-like protein; progressive ankylosis; progressive ankylosis homolog; progressive ankylosis protein; Progressive ankylosis protein homolog; UNQ241/PRO274
• Common Name: ANKH
• Gene Symbol: ANKH
• Conjugate: Unconjugated
• Species: Human
• Recombinant: Recombinant
• Protein Tag: His-ABP-tag
• Sequence: ACYVYRKQKKKMENESATEGEDSAMTDMPPTEEVTDIVEMREENE
• Content And Storage: -20°C, Avoid Freeze/Thaw Cycles
• Expression System: E. coli
• Form: Liquid
• Purity or Quality Grade: >80% by SDS-PAGE and Coomassie blue staining