ACROBiosystems Human AIMP1 / EMAP2 / SCYE1 Protein, His Tag

Product Code.	Quantity	unitSize
15876637	100 μg	100µg
15886637	1 mg	1mg

Product Code. 15876637 Supplier ACROBiosystems Supplier No. EM2H5142100UG

Description

Aminoacyl tRNA synthase complex-interacting multifunctional protein 1 (AIMP1) is also known as multisynthase complex auxiliary component p43 and endothelial monocyte-activating polypeptide II (EMAP-II). AIMP1 is a cytokine that may be induced by apoptosis and is also released from professional antigen-presenting cells such as dendritic cells. The release of AIMP1 renders the tumor-associated vasculature sensitive to tumor necrosis factor. Furthermore, AIMP1 binds tRNA and stimulates the catalytic activity of cytoplasmic arginyl-tRNA synthase. This protein possesses inflammatory cytokine activity. Also, AIMP1 negatively regulates TGF-beta signaling through stabilization of SMURF2 by binding to SMURF2 and inhibiting its SMAD7-mediated degradation.

This protein carries a polyhistidine tag at the N-terminus. The protein has a calculated MW of 35.2 kDa. The protein migrates as 36 kDa under reducing (R) condition (SDS-PAGE).

Specifications

• Accession Number: AAH14051.1
• Molecular Weight (g/mol): 35.2 kDa
• Quantity: 100 μg
• Source: Human AIMP1, His Tag (EM2-H5142) is expressed from E.coli cells. It contains AA Ala 2 - Lys 312 (Accession # Q12904-1).
• Immunogen: Ala 2 - Lys 312
• Storage Requirements: -20°C
• Gene Alias: AIMP1,EMAP2,EMAPII,HLD3,SCYE1,p43,EMAP-2,EMAP-II,AIMP-1
• Common Name: AIMP1
• Conjugate: Unconjugated
• Species: Human
• Protein Tag: His Tag
• Buffer: PBS, pH7.4
• Endotoxin Level: Less than 1.0 EU / μg by the LAL method.
• Expression System: E.coli
• Form: Powder
• Protein Subtype: Cytokines and Growth Factors
• Purity or Quality Grade: >95% as determined by SDS-PAGE