Invitrogen™ Human AGK (aa 88-172) Control Fragment Recombinant Protein

Product Code. 30200077

Brand: Invitrogen™ RP92596

Description

Recombinant Protein

Highest antigen sequence indentity to the following orthologs: Mouse (96%), Rat (96%). This recombinant protein control fragment may be used for blocking experiments with the corresponding antibody, PA5-54284 (PA5-54284. In IHC/ICC and WB experiments, we recommend a 100x molar excess of the protein fragment control based on the concentration and the molecular weight. Pre-incubate the antibody-protein control fragment mixture for 30 min at room temperature.

Lipid kinase that can phosphorylate both monoacylglycerol and diacylglycerol to form lysophosphatidic acid (LPA) and phosphatidic acid (PA), respectively. Does not phosphorylate sphingosine. Overexpression increases the formation and secretion of LPA, resulting in transactivation of EGFR and activation of the downstream MAPK signaling pathway, leading to increased cell growth.

Specifications

• Accession Number: Q53H12
• Concentration: ≥5.0 mg/mL
• For Use With (Application): Blocking Assay, Control
• Formulation: 1 M urea, PBS with no preservative; pH 7.4
• Gene ID (Entrez): 55750
• Name: Human AGK (aa 88-172) Control Fragment
• Quantity: 100 μL
• Regulatory Status: RUO
• Gene Alias: 2610037M15Rik; 6720408I04Rik; acylglycerol kinase; acylglycerol kinase, mitochondrial; Agk; AI465370; CATC5; CTRCT38; FLJ10842; hAGK; hsMuLK; MTDPS10; Mulk; multiple substrate lipid kinase; multi-substrate lipid kinase; RGD1562046
• Common Name: AGK
• Gene Symbol: AGK
• Conjugate: Unconjugated
• Species: Human
• Recombinant: Recombinant
• Protein Tag: His-ABP-tag
• Sequence: LHLSGMDVTIVKTDYEGQAKKLLELMENTDVIIVAGGDGTLQEVVTGVLRRTDEATFSKIPIGFIPLGETSSLSHTLFAESGNKV
• Content And Storage: -20°C, Avoid Freeze/Thaw Cycles
• Expression System: E. coli
• Form: Liquid
• Purity or Quality Grade: >80% by SDS-PAGE and Coomassie blue staining