Invitrogen™ HTRA3 Polyclonal Antibody

Rabbit Polyclonal Antibody

Brand:  Invitrogen™ PA5110869

Product Code. 17138793

Description

Immunogen sequence: ITRFLTEFQD KQIKDWKKRF IGIRMRTITP SLVDELKASN PDFPEVSSGI YVQEVAPNSP SQRGGIQDGD IIVKVNGRPL VDSSELQEAV LTESPLLLEV RRGNDDLLFS IAP Highest antigen sequence indentity to the following orthologs: Mouse - 89%, Rat - 90%.

HtrA3 belongs to the human high-temperature requirement factor A (HtrA) family. It is also called pregnancy-related serine protease. HtrA3 has two isoforms (long and short), which is produced by alternative splicing. Similar to HtrA1, HtrA3 binds to various TGF-beta proteins and inhibited the signaling of BMP-4, -2 and TGF-beta 1. HtrA3 does not inhibit signaling originated from a constitutively active BMP receptor, indicating that the inhibition occurred upstream of the cell surface receptor.

Specifications

• Antigen: HTRA3
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: HTRA3
• Gene Alias: 2210021K23Rik; 9530081K03Rik; High-temperature requirement factor A3; HtrA serine peptidase 3; Htra3; Pregnancy-related serine protease; probable serine protease HTRA3; Prsp; RGD1308120; Serine protease HTRA3; Tasp; Toll-associated serine protease
• Host Species: Rabbit
• Purification Method: Antigen affinity chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 94031
• Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
• Form: Liquid

• Applications: Immunohistochemistry (Paraffin)
• Concentration: 0.4 mg/mL
• Formulation: PBS with 40% glycerol and 0.02% sodium azide; pH 7.2
• Gene Accession No.: P83110
• Gene Symbols: HTRA3
• Immunogen: Recombinant Protein corresonding to Human HTRA3. Recombinant protein control fragment (Product #RP-91877).
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human
• Product Type: Antibody
• Isotype: IgG