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Invitrogen™ HTR1B Polyclonal Antibody
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Product Code. 11526242
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Quantity:
25 μg
Unit Size:
25µg
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Product Code. Quantity unitSize
11526242 25 μg 25µg
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Product Code. 11526242 Supplier Invitrogen™ Supplier No. PA120650

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Description

Rabbit Polyclonal Antibody

PA1-20650 detects 5-HT1B Receptor in human samples.

Serotonin (5-hydroxytryptamine, 5-HT), originally discovered as a serum factor plays important roles in regulating diverse biological processes in central and peripheral nervous systems, cardiovascular systems, and gastrointestinal systems. Molecular cloning studies have identified 5 receptors belonging to the 5-HT1 subtypes. These receptors are negatively coupled to adenylyl cyclase. Radioligand binding studies suggest the presence of 5-HT1B (formerly known as 5-HT1DbR) sites in substantia nigra, dorsal subiculum, globus pallidus, and superior collicum. In situ hybridization studies show abundance of 5-HT1BR mRNA in CA1 pyramidal cells of hippocampus, Purkinje cells of cerebellum, olfactory tubercle, subthalamic nucleus and somewhat lower levels in the caudate-putamen, cortical areas, thalamic and hypothalamic nuclei.
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Specifications

Antigen HTR1B
Applications Immunohistochemistry (Paraffin)
Classification Polyclonal
Concentration 1 mg/mL
Conjugate Unconjugated
Formulation PBS with 0.1% sodium azide
Gene HTR1B
Gene Accession No. O08892, P28222, P28334, P28564, P46636, P49144, P79250, P79399
Gene Alias 5-HT>1B> receptor; 5ht1b; 5-HT1B; 5-HT-1B; 5HT1B Receptor; 5-HT1B receptor; 5-HT1B serotonin receptor; 5-HT1DB; 5-HT-1D-beta; 5-hydroxytryptamine (serotonin ) receptor 1B; 5-hydroxytryptamine (serotonin) receptor 1B; 5-hydroxytryptamine (serotonin) receptor 1B, G protein-coupled; 5-hydroxytryptamine receptor 1B; HTR1B; HTR1D2; HTR1DB; S12; serotonin (5-hydroxytryptamine (5HT)) receptor type 1B; serotonin 1D beta receptor; Serotonin receptor 1B
Gene Symbols HTR1B
Host Species Rabbit
Immunogen Synthetic 16 amino acid peptide from 3rd cytoplasmic domain of human 5HT1B Receptor.
Purification Method Antigen affinity chromatography
Quantity 25 μg
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 100009594, 100689321, 100717602, 15551, 25075, 317707, 3351, 397563, 403741
Target Species Human, Mouse, Rat, Canine, Rabbit, Bovine, Hamster, Pig, Guinea Pig, Bat
Content And Storage Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Product Type Antibody
Form Liquid
Isotype IgG
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