Invitrogen™ HSPB11 Polyclonal Antibody

Rabbit Polyclonal Antibody

Brand:  Invitrogen™ PA5116808

Product Code. 17299303

Beskrivning

Positive Samples: A-549, 293T, Mouse kidney, Mouse brain, Rat thymus Immunogen sequence: MRKIDLCLSS EGSEVILATS SDEKHPPENI IDGNPETFWT TTGMFPQEFI ICFHKHVRIE RLVIQSYFVQ TLKIEKSTSK EPVDFEQWIE KDLVHTEGQL QNEEIVAHDG SATYLRFIIV SAFDHFASVH SVSAEGTVVS NLSS.

HSPB11 (Heat shock protein beta-11), also known as IFT25, was originally identified as a small heat shock protein. Recently it has been identified as a component of IFT complex B. It has been demonstrated that IFT25 is not required for ciliary assembly but is required for proper Hedgehog signaling, which in mammals occurs within cilia. Cilia lacking IFT25 have defects in the signal-dependent transport of multiple Hedgehog components and fail to activate the pathway upon stimulation.

Specifikationer

• Antigen: HSPB11
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: Hspb11
• Gene Alias: 2900042B11Rik; C1orf41; Heat shock protein; Heat shock protein beta-11; heat shock protein family B (small) member 11; heat shock protein family B (small), member 11; HSP; Hspb11; Hspb11 heat shock protein family B (small), member 11; HSPC034; HSPCO34; IFT25; intraflagellar transport 25 homolog; intraflagellar transport protein 25 homolog; Placental protein 25; placental protein 25 homolog; PP25
• Host Species: Rabbit
• Purification Method: Affinity chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 51668, 685284, 72938
• Content And Storage: -20°C, Avoid Freeze/Thaw Cycles
• Form: Liquid

• Applications: ELISA, Immunohistochemistry (Paraffin), Western Blot, Immunocytochemistry
• Concentration: 0.90 mg/mL
• Formulation: PBS with 50% glycerol and 0.01% thimerosal; pH 7.3
• Gene Accession No.: Q9D6H2, Q9Y547
• Gene Symbols: Hspb11
• Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 1-144 of human HSPB11 (NP_0572102).
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human, Mouse, Rat
• Product Type: Antibody
• Isotype: IgG