HSPA5 Mouse anti-Human, HRP, Clone:1H11-1H7, Abnova™

Mouse monoclonal antibody raised against human HSPA5.

Brand:  Abnova MAB17322.100ug

Product Code. 16169849

Description

When Chinese hamster K12 cells are starved of glucose, the synthesis of several proteins, called glucose-regulated proteins (GRPs), is markedly increased. Hendershot et al. (1994) [PubMed 8020977] pointed out that one of these, GRP78 (HSPA5), also referred to as ′immunoglobulin heavy chain-binding protein′ (BiP), is a member of the heat-shock protein-70 (HSP70) family and is involved in the folding and assembly of proteins in the endoplasmic reticulum (ER). Because so many ER proteins interact transiently with GRP78, it may play a key role in monitoring protein transport through the cell.[supplied by OMIM]

Specifications

• Antigen: HSPA5
• Classification: Monoclonal
• Conjugate: HRP
• Dilution: Immunocytochemistry (1:100)
  Immunofluorescence (1:100)
  Western Blot (1:2000)
  The optimal working dilution should be determined by the end user.
• Gene: HSPA5
• Host Species: Mouse
• Quantity: 100 μg
• Target Species: Human
• Product Type: Antibody
• Isotype: IgG2b

• Applications: Immunocytochemistry, Immunofluorescence, Western Blot
• Clone: 1H11-1H7
• Description: heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa)
• Formulation: In PBS, pH 7.4 (50% glycerol, 0.09% sodium azide)
• Gene Alias: BIP, FLJ26106, GRP78, MIF2
• Immunogen: His-tagged human HSPA5.
• Gene ID (Entrez): 3309
• Content And Storage: Store at -20°C.
• Form: Liquid