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Invitrogen™ HSP104 Polyclonal Antibody

Product Code. 11578731
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Quantity:
100 μL
Unit Size:
100µL
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11578731 100 μL 100µL
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Product Code. 11578731 Supplier Invitrogen™ Supplier No. PA3016A

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Description

Rabbit Polyclonal Antibody

PA3-016A detects HSP104 from yeast samples. This antibody does not detect HSP100 from prokaryotes, nor certain plants and insects including Drosophila. PA3-016A has been successfully used in Western blot procedures. By Western blot, this antibody detects a single ~104 kDa protein from yeast. The PA3-016A immunogen is a synthetic peptide corresponding to the C-terminal residues D(894) D D N E D S M E I D D D L D(908) of S. cerevisiae HSP104.

Heat shock proteins (HSP) are expressed in response to various biological stresses, including high temperatures. There are several major families of HSPs including HSP70, HSP90 and HSP100. The HSP100 proteins generally have amino acid sequences of about 900 residues and contain two nucleotide-binding sites. Within the HSP100 family of proteins, yeast express an ~104 kDa form which is necessary to protect cells from various stress conditions such as heat, heavy metals and ethanol, though mutation studies have shown that the protein is not required for normal growth. Yeast HSP104 has been shown to be a ClpB protein with significant sequence homology to E. coli ClpB, particularly in the two nucleotide-binding sites.
TRUSTED_SUSTAINABILITY

Specifications

Antigen HSP104
Applications Western Blot
Classification Polyclonal
Concentration Conc. Not Determined
Conjugate Unconjugated
Formulation Whole serum with 0.05% sodium azide
Gene HSP104
Gene Accession No. P31539
Gene Alias chaperone ATPase HSP104; Heat shock protein; Heat shock protein 104; HS104; HSP; HSP104; L0948; Protein aggregation-remodeling factor HSP104; YLL026W
Gene Symbols HSP104
Host Species Rabbit
Immunogen Synthetic peptide corresponding to C-terminal residues D(894) D D N E D S M E I D D D L D(908) of S. cerevisiae HSP104.
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 850633
Target Species Yeast
Content And Storage -20°C, Avoid Freeze/Thaw Cycles
Product Type Antibody
Form Liquid
Isotype IgG
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