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Description
This antibody detects the 65 kDa protein (Erythrocyte 65 kDa protein, P65).
WNK is a serine/threonine kinase that plays an important role in the regulation of electrolyte homeostasis, cell signaling, survival, and proliferation. Also, acts as an activator and inhibitor of sodium-coupled chloride cotransporters and potassium-coupled chloride cotransporters respectively. Activates SCNN1A, SCNN1B, SCNN1D, and SGK1. WNK localizes to a segment of kidney involved in salt, potassium, and pH homeostasis, the distal nephron. Mutations in the WNK gene result in Pseudohypaldosteronism and Neuropathy.
Specifications
Specifications
| Antigen | HSN2 |
| Applications | Western Blot, Immunohistochemistry (Paraffin) |
| Classification | Polyclonal |
| Concentration | 0.34 mg/mL |
| Conjugate | Unconjugated |
| Formulation | PBS with 50% glycerol and 0.02% sodium azide; pH 7.3 |
| Gene | WNK1 |
| Gene Accession No. | P83741, Q9H4A3 |
| Gene Alias | HSAN2, HSN2 |
| Gene Symbols | WNK1 |
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Product Title
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