Invitrogen™ HSD3B7 Polyclonal Antibody

Rabbit Polyclonal Antibody

Brand:  Invitrogen™ PA562204

Product Code. 15730002

Description

Immunogen sequence: VVRMLLQREP RLGELRVFDQ HLGPWLEELK TGPVRVTAIQ GDVTQAHEVA AAVAGAHVVI HTAGLVDVFG RASPKTIHEV NVQG Highest antigen sequence identity to the following orthologs: Mouse - 85%, Rat - 85%.

This gene encodes an enzyme which is involved in the initial stages of the synthesis of bile acids from cholesterol and a member of the short-chain dehydrogenase/reductase superfamily. The encoded protein is a membrane-associated endoplasmic reticulum protein which is active against 7-alpha hydrosylated sterol substrates. Mutations in this gene are associated with a congenital bile acid synthesis defect which leads to neonatal cholestasis, a form of progressive liver disease. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Dec 2008].

Specifications

• Antigen: HSD3B7
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: HSD3B7
• Gene Alias: 3 beta-hydroxy-delta 5-C27-steroid oxidoreductase; 3 beta-hydroxysteroid dehydrogenase type 7; 3 beta-hydroxysteroid dehydrogenase type VII; 3-beta-HSD VII; 3-beta-hydroxy-Delta(5)-C27 steroid oxidoreductase; AI195443; BB098564; C(27) 3-beta-HSD; C(27)-3BETA-HSD; CBAS1; Cca2; cholest-5-ene-3-be; cholest-5-ene-3-beta,7-alpha-diol 3-beta-dehydrogenase; Confluent 3Y1 cell-associated 2; HSD3B7; hsd3b7 {ECO:0000312; hydroxy-delta-5-steroid dehydrogenase, 3 beta- and steroid delta-isomerase 7; PFIC4; RGD:628727}; SDR11E3; short chain dehydrogenase/reductase family 11E, member 3
• Host Species: Rabbit
• Purification Method: Antigen affinity chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 80270
• Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
• Form: Liquid

• Applications: Immunohistochemistry (Paraffin), Immunocytochemistry
• Concentration: 0.2 mg/mL
• Formulation: PBS with 40% glycerol and 0.02% sodium azide; pH 7.2
• Gene Accession No.: Q9H2F3
• Gene Symbols: HSD3B7
• Immunogen: Recombinant protein corresponding to Human HSD3B7. Recombinant protein control fragment (Product #RP-101137).
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human
• Product Type: Antibody
• Isotype: IgG