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Invitrogen™ HRH1 Polyclonal Antibody

Description
Positive test controls include: U-251MG, Mouse liver, Rat liver. Immunogen sequence: KPGKESPWEV LKRKPKDAGG GSVLKSPSQT PKEMKSPVVF SQEDDREVDK LYCFPLDIVH MQAAAEGSSR DYVAVNRSHG QLKTDEQGLN T.
Histamine is a ubiquitous messenger molecule released from mast cells, enterochromaffin-like cells, and neurons. Its various actions are mediated by histamine receptors H1, H2, H3 and H4. This gene was thought to be intronless until recently. The protein encoded by this gene is an integral membrane protein and belongs to the G protein-coupled receptor superfamily. It mediates the contraction of smooth muscles, the increase in capillary permeability due to contraction of terminal venules, the release of catecholamine from adrenal medulla, and neurotransmission in the central nervous system. Multiple alternatively spliced variants, encoding the same protein, have been identified.
Specifications
Specifications
| Antigen | HRH1 |
| Applications | ELISA, Western Blot, Immunocytochemistry |
| Classification | Polyclonal |
| Concentration | 1.76 mg/mL |
| Conjugate | Unconjugated |
| Formulation | PBS with 50% glycerol and 0.01% thimerosal; pH 7.3 |
| Gene | HRH1 |
| Gene Accession No. | P31390, P35367, P70174 |
| Gene Alias | Bordetella pertussis induced histamine sensitization; Bphs; H1 receptor; H1R; H1-R; HH1R; Hir; hisH1; Hisr; histamine H1 receptor; Histamine H1-R; histamine receptor; histamine receptor H 1; histamine receptor H1; histamine receptor, subclass H1; Hrh1 |
| Gene Symbols | HRH1 |
| Show More |
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