Invitrogen™ HRH1 Polyclonal Antibody

Rabbit Polyclonal Antibody

Brand:  Invitrogen™ PA5120691

Product Code. 17702094

Description

Positive test controls include: U-251MG, Mouse liver, Rat liver. Immunogen sequence: KPGKESPWEV LKRKPKDAGG GSVLKSPSQT PKEMKSPVVF SQEDDREVDK LYCFPLDIVH MQAAAEGSSR DYVAVNRSHG QLKTDEQGLN T.

Histamine is a ubiquitous messenger molecule released from mast cells, enterochromaffin-like cells, and neurons. Its various actions are mediated by histamine receptors H1, H2, H3 and H4. This gene was thought to be intronless until recently. The protein encoded by this gene is an integral membrane protein and belongs to the G protein-coupled receptor superfamily. It mediates the contraction of smooth muscles, the increase in capillary permeability due to contraction of terminal venules, the release of catecholamine from adrenal medulla, and neurotransmission in the central nervous system. Multiple alternatively spliced variants, encoding the same protein, have been identified.

Specifications

• Antigen: HRH1
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: HRH1
• Gene Alias: Bordetella pertussis induced histamine sensitization; Bphs; H1 receptor; H1R; H1-R; HH1R; Hir; hisH1; Hisr; histamine H1 receptor; Histamine H1-R; histamine receptor; histamine receptor H 1; histamine receptor H1; histamine receptor, subclass H1; Hrh1
• Host Species: Rabbit
• Purification Method: Affinity Chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 15465, 24448, 3269
• Content And Storage: -20°C, Avoid Freeze/Thaw Cycles
• Form: Liquid

• Applications: ELISA, Western Blot, Immunocytochemistry
• Concentration: 1.76 mg/mL
• Formulation: PBS with 50% glycerol and 0.01% thimerosal; pH 7.3
• Gene Accession No.: P31390, P35367, P70174
• Gene Symbols: HRH1
• Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 250-340 of human HRH1 (NP_000852.1).
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human, Mouse, Rat
• Product Type: Antibody
• Isotype: IgG