Invitrogen™ HRG Polyclonal Antibody

Rabbit Polyclonal Antibody

Brand:  Invitrogen™ PA597051

Product Code. 16579881

Description

Immunogen sequence: SPTDCSAVEP EAEKALDLIN KRRRDGYLFQ LLRIADAHLD RVENTTVYYL VLDVQESDCS VLSRKYWNDC EPPDSRRPSE IVIGQCKVIA TRHSHESQDL RVIDFNCTTS SVSSALANTK DSPVLIDFFE DTERYRKQAN KALEKYKEEN DDFASFRVDR IERVARVRGG EGTGYFVDFS VRNCPRHHFP RHPNVFGFCR ADLFYDVEAL DLESPKNLVI NCEVFDPQEH ENINGVPPHL G; Positive Samples: Mouse pancreas.

HRG contains two cystatin-like domains and is located in plasma and platelets. The physiological function has not been determined but it is known that the protein binds heme, dyes and divalent metal ions. It can inhibit rosette formation and interacts with heparin, thrombospondin and plasminogen. Two of the protein's effects, the inhibition of fibrinolysis and the reduction of inhibition of coagulation, indicate a potential prothrombotic effect. Mutations in this gene lead to thrombophilia due to abnormal histidine-rich glycoprotein levels.

Specifications

• Antigen: HRG
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: HRG
• Gene Alias: AI265597; AW413091; D16jh2; D18020; DKFZp779H1622; histidine rich glycoprotein; histidine-proline-rich glycoprotein; Histidine-rich glycoprotein; histidine-rich glycoprotein 1; HPRG; HRG; HRG1; Hrgp; THPH11
• Host Species: Rabbit
• Purification Method: Affinity chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 171016, 94175
• Content And Storage: -20°C, Avoid Freeze/Thaw Cycles
• Form: Liquid

• Applications: ELISA, Western Blot
• Concentration: 1.78 mg/mL
• Formulation: PBS with 50% glycerol and 0.02% sodium azide; pH 7.3
• Gene Accession No.: Q99PS8, Q9ESB3
• Gene Symbols: HRG
• Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 20-260 of human HRG (NP_0004031).
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Mouse, Rat
• Product Type: Antibody
• Isotype: IgG