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HPOB, MedChemExpress

Product Code. 16483827
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Product Code. 16483827

Brand: Medchem Express HY19747

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Description

MedChemExpress HPOB is a highly potent and selective inhibitor of HDAC6 with an IC50 of 56 nM. HPOB displays >30 fold less potent against other HDACs. HPOB enhances the effectiveness of DNA-damaging anticancer agents in transformed cells but not normal cells. HPOB does not block the ubiquitin-binding activity of HDAC6.

HPOB is a highly potent and selective inhibitor of HDAC6 with an IC50 of 56 nM. HPOB displays >30 fold less potent against other HDACs. HPOB enhances the effectiveness of DNA-damaging anticancer agents in transformed cells but not normal cells. HPOB does not block the ubiquitin-binding activity of HDAC6.

Specifications

Chemical Name or Material HPOB
Physical Form Solid
CAS 1429651-50-2
Color Pink
Quantity 50 mg
Purity Grade Notes Research
Molecular Formula C17H18N2O4
For Use With (Application) Cancer-programmed cell death
Solubility Information DMSO : 50 mg/mL (159.06 mM; Need ultrasonic)
SMILES O=C(N(CCO)C1=CC=CC=C1)CC2=CC=C(C(NO)=O)C=C2
Molecular Weight (g/mol) 314.34
Formula Weight 314.34
Percent Purity 95.0%
Grade Research
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Research purposes only

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