Invitrogen™ HPa1 Polyclonal Antibody

Rabbit Polyclonal Antibody

Brand:  Invitrogen™ PA595775

Product Code. 16508621

Description

Positive Samples: Jurkat, BxPC-3, A-431, mouse spleen, mouse lung, rat spleen, rat lung; Cellular Location: Lysosome membrane, Nucleus, Peripheral membrane protein Immunogen sequence: QDVVDLDFFT QEPLHLVSPS FLSVTIDANL ATDPRFLILL GSPKLRTLAR GLSPAYLRFG GTKTDFLIFD PKKESTFEER SYWQSQVNQD ICKYGSIPPD VEEKLRLEWP YQEQLLLREH YQKKFKNSTY SRSSVDVLYT FANCSGLDLI FGLNALLRTA DLQWNSSNAQ LLLDYCSSKG YNISWELGNE PNSFLKKADI FINGSQLGED FIQLHKLLRK STFKNAKLYG PDVGQPRRKT.

Stem cells offer a therapeutic promise for many diseases. In the case of diabetes, stem cells offer the promise that beta cells may be generated ex vivo for the possible transplantation and cure of Type I diabetes (Couri CE, et al. ). For this to happen, stem cells will need to be isolated and expanded, they will need to be differentiated toward the beta cell lineage, and the differentiated cell progeny used for transplantation may need to be isolated from complex cell mixtures following differentiation. Appropriate markers targeting cell surface molecules on developing and mature pancreatic cells will be required for such research.

Specifications

• Antigen: HPa1
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: HPSE
• Gene Alias: Endo-glucoronidase; endoglycosidase heparanase; HEP; Heparanase; Heparanase 50 kDa subunit; Heparanase 8 kDa subunit; Heparanase-1; heparanase-like; Hpa; HPA1; HPR1; HPSE; HPSE1; HSE1
• Host Species: Rabbit
• Purification Method: Affinity Chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 10855, 15442, 64537
• Content And Storage: -20°C, Avoid Freeze/Thaw Cycles
• Form: Liquid

• Applications: ELISA, Immunohistochemistry (Paraffin), Western Blot, Immunocytochemistry, Western Blot
• Concentration: 1.89 mg/mL
• Formulation: PBS with 50% glycerol and 0.09% sodium azide; pH 7.3
• Gene Accession No.: Q6YGZ1, Q71RP1, Q9Y251
• Gene Symbols: HPSE
• Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 36-275 of human Heparanase 1 (NP_0010920101).
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human, Mouse, Rat
• Product Type: Antibody
• Isotype: IgG