Invitrogen™ HOXC12 Polyclonal Antibody

Rabbit Polyclonal Antibody

Brand:  Invitrogen™ PA5103893

Product Code. 16640345

Description

Antibody detects endogenous levels of total HOXC12.

The Homeobox (Hox) proteins are a family of transcription factors that play a role in development and cellular differentiation by regulating downstream target genes. Specifically, the Hox proteins direct DNA-protein and protein-protein interactions that assist in determining the morphologic features associated with the anterior-posterior body axis. Hox proteins are involved in controlling axial patterning, leukemias and hereditary malformations. In mammals, there are four gene clusters encoding Hox proteins, namely HoxA, HoxB, HoxC and HoxD, that are located on different chromosomes, each consisting of 9-11 tandemly arranged genes. HoxC12 (Homeobox C12), also known as Hox3, Hox3F or HOC3F, is a member of the Abd-B homeobox (Hox) family and is encoded by a gene from the HoxC cluster. HoxC12 is a 282 amino acid long nuclear protein that contains one homeobox DNA-binding domain.

Specifications

• Antigen: HOXC12
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: HOXC12
• Gene Alias: HOC3F; homeo box C12; homeobox C12; homeobox protein Hox-3.8; Homeobox protein Hox-3F; Homeobox protein Hox-C12; Homeobox protein Hox-C12 (Hox-3F); HOX3; Hox-3.8; HOX3F; HOXC12; Hoxc-12
• Host Species: Rabbit
• Purification Method: Affinity chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 15421, 300262, 3228
• Content And Storage: -20°C
• Form: Liquid

• Applications: Western Blot
• Concentration: 1 mg/mL
• Formulation: PBS with 50% glycerol and 0.02% sodium azide; pH 7.4
• Gene Accession No.: P31275, Q8K5B8
• Gene Symbols: HOXC12
• Immunogen: A synthesized peptide derived from human HOXC12(Accession P31275), corresponding to amino acid residues P65-D115.
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human, Mouse, Rat
• Product Type: Antibody
• Isotype: IgG