Invitrogen™ HOXB7 Monoclonal Antibody (864614)

Mouse Monoclonal Antibody

Brand:  Invitrogen™ MA561897

Product Code. 30534947

Description

Reconstitute with sterile PBS to a final concentration of 0.5 mg/mL.

The homeobox genes encode transcription factors that regulate developmental processes such as body patterning and organogenesis. The mammalian HOX gene complex consists of 39 genes that are located on 4 linkage groups (clusters), dispersed over 4 chromosomes (HOXA, HOXB, HOXC and HOXD). HOXB7 is expressed in most malignant T-cell lines and CD4-positive peripheral blood cells, and is constitutively expressed in both melanoma primary lesions and cell lines. HOXB7 binds to and transactivates bFGF in melanoma cell lines but SkBr3 breast adenocarcinoma is negative for the expression of both HOXB7 and bFGF genes. HOXB7 may be a key activator of tumor-associated neoangiogenesis.

Specifications

• Antigen: HOXB7
• Classification: Monoclonal
• Concentration: 0.5 mg/mL
• Formulation: PBS with trehalose and no preservative
• Gene Accession No.: P09629
• Gene Symbols: Hoxb7
• Immunogen: E. coli-derived recombinant human HOXB7, Met1-Asn123.
• Quantity: 100 μg
• Primary or Secondary: Primary
• Target Species: Human
• Product Type: Antibody
• Isotype: IgG1

• Applications: Immunocytochemistry
• Clone: 864614
• Conjugate: Unconjugated
• Gene: Hoxb7
• Gene Alias: AI325018; HHO.C1; homeo box 2C; homeo box B7; homeo box c1 protein; homeobox B7; homeobox gene B7; homeobox protein HHO.C1; Homeobox protein Hox-2.3; homeobox protein Hox-2C; Homeobox protein Hox-B7; homeobox protein MH-22B; Homeobox protein MuB1; homeobox protein R1B; HOX2; Hox-2.3; Hox-23; HOX2C; Hox2r1b; Hoxb7; Hoxb-7; R1b
• Host Species: Mouse
• Purification Method: Protein A/G
• Regulatory Status: RUO
• Gene ID (Entrez): 3217
• Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
• Form: Lyophilized