Invitrogen™ HOXB5 Polyclonal Antibody

Rabbit Polyclonal Antibody

Brand:  Invitrogen™ PA536381

Product Code. 15517651

Description

This antibody detects endogenous protein at a molecular weight of 30 kDa. Purity is >95% by SDS-PAGE.

The Hox proteins are a family of transcription factors that play a role in development and cellular differentiation by regulating downstream target genes. Specifically, the Hox proteins direct DNA-protein and protein-protein interactions that assist in determining the morphologic features associated with the anterior-posterior body axis. Hox proteins are involved in controlling axial patterning, leukemias and hereditary malformations. HoxB5 (homeobox protein Hox-B5), also known as HOX2, HU-1, HOX2A, Hox2.1 or HHO.C10, is a member of the Antp homeobox (Hox) family. It is a 269 amino acid long nuclear protein expressed in the central nervous system. HoxB5 contains one homeobox DNAbinding domain and plays a role in the regulation of lung and gut development, providing cells with positional identities on the anterior-posterior body axis.

Specifications

• Antigen: HOXB5
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: HOXB5
• Gene Alias: AI385717; HHO.C10; homeo box 2A; homeo box B5; homeobox B5; homeobox protein H24.1; Homeobox protein HHO.C10; homeobox protein Hox-2.1; Homeobox protein Hox-2A; homeobox protein Hox-B5; Homeobox protein Hu-1; homeobox protein Mu-1; HOX2; Hox2.1; Hox-2.1; HOX2A; HOXB5; Hoxb-5; HU-1; RGD1562292
• Host Species: Rabbit
• Purification Method: Antigen affinity chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 15413, 3215, 497987
• Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
• Form: Liquid

• Applications: Western Blot
• Concentration: 1 mg/mL
• Formulation: PBS with 0.05% sodium azide; pH 7.2
• Gene Accession No.: P09067, P09079
• Gene Symbols: HOXB5
• Immunogen: Synthetic peptide corresponding to amino acids 161-210 of human Hox-B5.
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human, Mouse, Rat
• Product Type: Antibody
• Isotype: IgG