Invitrogen™ HOXB4 Recombinant Rabbit Monoclonal Antibody (23GB6620), Invitrogen™

Rabbit Recombinant Monoclonal Antibody

Brand:  Invitrogen™ MA553079

Product Code. 30089462

Description

HOX homeobox genes play a role both in the early stem cell function as well as in later stages of hematopoietic differentiation. HOXB4, specifically, is a homeotic selector gene implicated in self-renewal of definitive HSCs. Expression of HOXB4 in primitive progenitors combined with culture on hematopoietic stroma induced a switch to the definitive HSC phenotype. Activation of WNT signaling in HSCs induced increased expression of HOXB4. Perturbations of HOX gene expression can cause leukemia.

Specifications

• Antigen: HOXB4
• Classification: Recombinant Monoclonal
• Conjugate: Unconjugated
• Gene: HOXB4
• Gene Alias: homeo box 2F; homeo box B4; homeo box B4a; homeobox B4; homeobox B4a; homeobox gene B-4; homeobox protein Hox-2.6; Homeobox protein Hox-2F; homeobox protein Hox-B4; Homeobox protein Hox-B4a; homeobox protein Zf-13; HOX2; Hox-2.6; HOX2F; Hoxb4; HOX-B4; Hoxb-4; Hoxb4 protein; hoxb4a; Hoxb4a variant 2; RGD1560113; sb:eu512; Z-17; zf13; ZF-13
• Host Species: Rabbit
• Purification Method: Affinity chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 3214, 497988
• Content And Storage: -20°C
• Form: Liquid

• Applications: Flow Cytometry, Western Blot, Immunocytochemistry
• Clone: 23GB6620
• Formulation: PBS with 50% glycerol and 0.02% sodium azide; pH 7.4
• Gene Accession No.: P17483
• Gene Symbols: HOXB4
• Immunogen: A synthesized peptide derived from human HOXB4 (21-55AA).
• Quantity: 20 μL
• Primary or Secondary: Primary
• Target Species: Human, Rat
• Product Type: Antibody
• Isotype: IgG