Invitrogen™ hnRNP L Monoclonal Antibody (4D11)

Mouse Monoclonal Antibody

Brand:  Invitrogen™ MA126745

Product Code. 11549542

Description

Recommended positive controls: MDBK. A band of ~65 kDa can be detected.

Heterogeneous nuclear RNAs (hnRNAs) which include mRNA precursors and mature mRNAs are associated with specific proteins to form heterogenous ribonucleoprotein (hnRNP) complexes. Heterogeneous nuclear ribonucleoprotein L is among the proteins that are stably associated with hnRNP complexes and along with other hnRNP proteins is likely to play a major role in the formation, packaging, processing, and function of mRNA. Heterogeneous nuclear ribonucleoprotein L is present in the nucleoplasm as part of the HNRP complex. HNRP proteins have also been identified outside of the nucleoplasm. Exchange of hnRNP for mRNA-binding proteins accompanies transport of mRNA from the nucleus to the cytoplasm. Since HNRP proteins have been shown to shuttle between the nucleus and the cytoplasm, it is possible that they also have cytoplasmic functions. Two transcript variants encoding different isoforms have been found for this gene.

Specifications

• Antigen: hnRNP L
• Classification: Monoclonal
• Concentration: 2.1 mg/mL
• Formulation: PBS with 15mM sodium azide; pH 7.4
• Gene Accession No.: P14866, Q8R081
• Gene Symbols: HNRNPL
• Immunogen: HnRNP proteins.
• Quantity: 50 μL
• Primary or Secondary: Primary
• Target Species: Amphibian, Bovine, Chicken, Human, Mouse, Monkey
• Product Type: Antibody
• Isotype: IgG1

• Applications: ELISA, Immunoprecipitation, Western Blot, Immunocytochemistry
• Clone: 4D11
• Conjugate: Unconjugated
• Gene: HNRNPL
• Gene Alias: C79783; D830027H13Rik; Fblim1; FLJ35509; Heterogeneous nuclear ribonucleoprotein L; heterogenous nuclear ribonucleoprotein L; hnRNP L; Hnrnpl; hnRNP-L; Hnrpl; P/OKcl.14
• Host Species: Mouse
• Purification Method: Protein A
• Regulatory Status: RUO
• Gene ID (Entrez): 101750874, 15388, 3191, 504520
• Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
• Form: Liquid