hnRNP C Polyclonal Antibody, Invitrogen™

Rabbit Polyclonal Antibody

Brand:  Invitrogen PA522280

Product Code. 13259718

Description

Recommended positive controls: Raji, Neuro2A, NIH-3T3, BCL-1, Raw264.7, C2C12, PC-12, Rat2. Predicted reactivity: Mouse (100%), Rat (100%), Xenopus laevis (88%), Pig (100%), Rabbit (92%), Rhesus Monkey (100%), Chimpanzee (100%), Bovine (100%). Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.

This gene belongs to the subfamily of ubiquitously expressed heterogeneous nuclear ribonucleoproteins (hnRNPs). The hnRNPs are RNA binding proteins and they complex with heterogeneous nuclear RNA (hnRNA). These proteins are associated with pre-mRNAs in the nucleus and appear to influence pre-mRNA processing and other aspects of mRNA metabolism and transport. While all of the hnRNPs are present in the nucleus, some seem to shuttle between the nucleus and the cytoplasm. The hnRNP proteins have distinct nucleic acid binding properties. The protein encoded by this gene can act as a tetramer and is involved in the assembly of 40S hnRNP particles. Multiple transcript variants encoding at least two different isoforms have been described for this gene.

Specifications

• Antigen: hnRNP C
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: HNRNPC
• Gene Alias: AL022939; C1; C2; D14Wsu171e; heterogeneous nuclear ribonucleoprotein C; heterogeneous nuclear ribonucleoprotein C (C1/C2); heterogeneous nuclear ribonucleoprotein C1; heterogeneous nuclear ribonucleoprotein C2; heterogeneous nuclear ribonucleoproteins C1/C2; heterogeneous ribonucleoprotein C1/C2; HNRNP; hnRNP C; hnRNP C protein C-terminal fragment (158 AA); hnRNP C1 / hnRNP C2; hnRNP C1/C2; hnRNP C2; hnRNP core protein C; Hnrnpc; hnrnp-C; hnRNPC1; hnRNPC2; HNRPC; Hnrpc1; Hnrpc2; nuclear ribonucleoprotein particle C1 protein; nuclear ribonucleoprotein particle C2 protein; snoRNA MBI-122; SNRPC
• Host Species: Rabbit
• Purification Method: Antigen affinity chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 15381, 290046, 3183
• Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
• Form: Liquid

• Applications: Immunocytochemistry, Immunohistochemistry (Paraffin), Immunoprecipitation, Western Blot
• Concentration: 0.79 mg/mL
• Formulation: 0.1M tris glycine with 10% glycerol and 0.01% thimerosal; pH 7
• Gene Accession No.: G3V9R8, P07910, Q9Z204
• Gene Symbols: HNRNPC
• Immunogen: Recombinant protein fragment contain a sequence corresponding to a region within amino acids 1 and 142 (P07910) of hnRNP C1/C2
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human, Mouse, Rat
• Product Type: Antibody
• Isotype: IgG