Invitrogen™ HNF4A Polyclonal Antibody

Rabbit Polyclonal Antibody

Brand:  Invitrogen™ PA582159

Product Code. 16359124

Description

Immunogen sequence: LLQEMLLGGS PSDAPHAHHP LHPHLMQEHM GTNVIVANTM PTHLSNGQMC EWPRPRGQAA TPETPQPSPP GGSGSEPYKL LPGAVATIVK PLSAIPQPTI TKQEV Highest antigen sequence indentity to the following orthologs: Mouse - 91%, Rat - 92%.

Hepatocyte nuclear factor 4 alpha (HNF4 alpha) is an orphan nuclear receptor. HNF4a is expressed in the liver, kidney, intestine, and pancreas. Mutation of HNF4a in humans has been associated with maturity-onset diabetes of the young type 1 (MODY1). HNF4 binds to DNA as an exclusive homodimer. The HNF4a gene is alternatively spliced and may generate up to nine different isoforms, HNF4a1 through HNF4a9.

Specifications

• Antigen: HNF4A
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: HNF4A
• Gene Alias: alpha transcription factor 4; FLJ39654; FRTS4; hepatic nuclear factor 4 alpha; hepatic nuclear factor 4, alpha; hepatocyte nuclear factor 4 alpha; hepatocyte nuclear factor 4, alpha; hepatocyte nuclear factor 4-alpha; HNF4; Hnf-4; HNF4 alpha; Hnf4a; HNF4a7; HNF4a8; HNF4a9; Hnf4alpha; HNF-4-alpha; HNF4-alpha; HNF4alpha10; HNF4alpha10/11/12; HNF4alpha11; HNF4alpha12; MODY; MODY1; NR2A1; NR2A21; Nuclear receptor 2A1; nuclear receptor subfamily 2 group A member 1; TCF; TCF14; TCF-14; Transcription factor 14; transcription factor HNF-4
• Host Species: Rabbit
• Purification Method: Antigen affinity chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 3172
• Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
• Form: Liquid

• Applications: ChIP Assay, Immunohistochemistry (Paraffin), Western Blot, Immunocytochemistry
• Concentration: 0.10 mg/mL
• Formulation: PBS with 40% glycerol and 0.02% sodium azide; pH 7.2
• Gene Accession No.: P41235
• Gene Symbols: HNF4A
• Immunogen: Recombinant protein corresponding to Human HNF4A. Recombinant protein control fragment (Product #RP-102324).
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human
• Product Type: Antibody
• Isotype: IgG