missing translation for 'onlineSavingsMsg'
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Description
This is a rabbit polyclonal antibody raised against the N-terminal region of human HNF1B. HNF1B exists some isoforms with MW of 61 kDa, 58 kDa, 46 kDa, and 44 kDa.
Hepatocyte Nuclear Factor 1 (HNF1, Homeoprotein LFB3, Transcription factor 2, TCF2, Variant hepatic nuclear factor) is a member of the homeodomain-containing superfamily of transcription factors. It is a liver-specific factor of the homeobox-containing basic helix-turn-helix family. The protein binds to DNA as either a homodimer, or a heterodimer with the related protein hepatocyte nuclear factor 1-alpha. HNF1has been shown to function in nephron development and regulates development of the embryonic pancreas. Mutations in the gene result in renal cysts and diabetes syndrome and noninsulin-dependent diabetes mellitus, and expression of the gene is altered in some types of cancer. Multiple transcript variants encoding different isoforms have been found for this gene.
Specifications
Specifications
| Antigen | HNF1B |
| Applications | Immunohistochemistry (Paraffin), Western Blot, Immunofluorescence, Immunocytochemistry |
| Classification | Polyclonal |
| Concentration | 0.28 mg/mL |
| Conjugate | Unconjugated |
| Formulation | PBS with 50% glycerol and 0.1% sodium azide; pH 7.3 |
| Gene | HNF1B |
| Gene Accession No. | P23899, P27889, P35680 |
| Gene Alias | FJHN, HNF 1 beta, HNF 1B, HNF1 homeobox B, HNF1B, HNF1beta, HNF2, Homeoprotein LFB3, HPC11, LF B3, LFB3, MODY5, TCF 2, TCF2, Transcription factor 2, VHNF1 |
| Gene Symbols | Hnf1b |
| Show More |
Product Title
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