Invitrogen™ HNF1A Polyclonal Antibody

Rabbit Polyclonal Antibody

Brand:  Invitrogen™ PA535356

Product Code. 15382254

Description

This antibody is predicted to react with rat based on sequence homology.

This gene is expressed ubiquitously with higher levels in fetal than in adult tissues. It encodes a protein sharing 93% sequence identity with the mouse protein. Wolf-Hirschhorn syndrome (WHS) is a malformation syndrome associated with a hemizygous deletion of the distal short arm of chromosome 4. This gene is mapped to the 165 kb WHS critical region, and may play a role in the phenotype of the WHS or Pitt-Rogers-Danks syndrome. The encoded protein is found to be capable of reacting with HLA-A2-restricted and tumor-specific cytotoxic T lymphocytes, suggesting a target for use in specific immunotherapy for a large number of cancer patients. This protein has also been shown to be a member of the NELF (negative elongation factor) protein complex that participates in the regulation of RNA polymerase II transcription elongation.

Specifications

• Antigen: HNF1A
• Classification: Polyclonal
• Formulation: PBS with 0.09% sodium azide; pH 7.4
• Gene Accession No.: P20823, P22361
• Gene Symbols: Hnf1a
• Immunogen: KLH conjugated synthetic peptide between 177-205 amino acids from the central region of human HNF1A.
• Quantity: 400 μL
• Primary or Secondary: Primary
• Target Species: Human, Mouse
• Product Type: Antibody
• Isotype: IgG

• Applications: Western Blot, Immunocytochemistry
• Conjugate: Unconjugated
• Gene: Hnf1a
• Gene Alias: AI323641; albumin proximal factor; hepatic nuclear factor 1; hepatic nuclear factor-1-alpha; hepatocyte nuclear factor 1; hepatocyte nuclear factor 1-alpha; Hepatocyte nuclear factor 1-alpha-A; HNF1; Hnf-1; hnf-1 alpha; HNF1 homeobox A; HNF1 homeobox A L homeolog; HNF1 homeobox A S homeolog; HNF1[a]; hnf1a; Hnf-1a; hnf1-a; hnf1a.L; hnf1a.S; HNF-1A-A; hnf1a-a; hnf1a-b; Hnf1alpha; HNF-1-alpha; HNF1-alpha; HNF-1-alpha-A; I79_010330; IDDM20; interferon production regulator factor; LFB1; LF-B1; LF-B1 hepatic nuclear factor (HNF1): albumin proximal factor also TCF1; LF-B1, hepatic nuclear factor (HNF1): albumin proximal factor, also TCF1; lfb1a; LFB1a1; Liver-specific transcription factor LF-B1; MODY3; TCF1; Tcf-1; TCF-1-A; tcf1-a; transcription factor 1; Transcription factor 1 hepatic; Transcription factor 1, hepatic; transcription factor 1, transcription factor LFB1 /HNF1; transcription factor 1-A; XELAEV_18010473mg; XLFB1; XLFB1a; XLFB1b
• Host Species: Rabbit
• Purification Method: Antigen affinity chromatography, Protein A
• Regulatory Status: RUO
• Gene ID (Entrez): 21405, 6927
• Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
• Form: Liquid