HMGXB3 Polyclonal Antibody, Invitrogen™

Rabbit Polyclonal Antibody

Brand:  Invitrogen PA538668

Product Code. 15585581

Description

HMGB3, also known as High mobility group protein B3, is a DNA associated protein that binds preferentially single-stranded DNA and unwinds double stranded DNA. This transcription factor belongs to the HMGB family and high mobility group (HMG) protein superfamily and contains two HMG box DNA-binding domains. Like other members of the family, HMGB3 plays a fundamental role in DNA replication, nucleosome assembly and transcription. Other functions include regulation of balance between hematopoietic stem cell self-renewal and differentiation and may also be required during embryonic development. HMGB3 is predomitly expressed in placenta.

Specifications

• Antigen: HMGXB3
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: HMGXB3
• Gene Alias: HMG-2a, HMG-4, HMG2A, HMG4, high mobility group protein 2a, high mobility group protein 4, high mobility group protein B3, high-mobility group (nonhistone chromosomal) protein 4, high-mobility group box 3, non-histone chromosomal protein
• Host Species: Rabbit
• Purification Method: Antigen affinity chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 22993
• Content And Storage: -20°C
• Form: Liquid

• Applications: Immunohistochemistry (Paraffin)
• Concentration: 1 mg/mL
• Formulation: Dulbecco′s PBS with 150mM NaCl, 50% glycerol and 0.02% sodium azide; pH 7.4
• Gene Accession No.: Q12766
• Gene Symbols: HMGXB3
• Immunogen: A synthetic peptide derived from the internal region of human SMF
• Quantity: 100 μg
• Primary or Secondary: Primary
• Target Species: Human
• Product Type: Antibody
• Isotype: IgG