Invitrogen™ HMGN3 Polyclonal Antibody

Rabbit Polyclonal Antibody

Brand:  Invitrogen™ PA551183

Product Code. 15655105

Description

The antibody detects endogenous levels of total HMGN3 protein.

Binds to nucleosomes, regulating chromatin structure and consequently, chromatin-dependent processes such as transcription, DNA replication and DNA repair. Affects both insulin and glucagon levels and modulates the expression of pancreatic genes involved in insulin secretion. Regulates the expression of the glucose transporter SLC2A2 by binding specifically to its promoter region and recruiting PDX1 and additional transcription factors. Regulates the expression of SLC6A9, a glycine transporter which regulates the glycine concentration in synaptic junctions in the central nervous system, by binding to its transcription start site. May play a role in ocular development and astrocyte function.

Specifications

• Antigen: HMGN3
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: HMGN3
• Gene Alias: 1110002A15Rik; 6330514M13Rik; BB071015; high mobility group nucleosomal binding domain 3; high mobility group nucleosome-binding domain-containing protein 3; HMGN3; PNAS-24; PNAS-25; thyroid hormone receptor interacting protein 7; Thyroid receptor-interacting protein 7; TR-interacting protein 7; TRIP7; TRIP-7
• Host Species: Rabbit
• Purification Method: Antigen affinity chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 9324, 94353
• Content And Storage: -20°C
• Form: Liquid

• Applications: Immunohistochemistry, Western Blot
• Concentration: 1.3 mg/mL
• Formulation: PBS with 40% glycerol and 0.05% sodium azide; pH 7.4
• Gene Accession No.: Q15651, Q9DCB1
• Gene Symbols: HMGN3
• Immunogen: Full length fusion protein of human HMGN3.
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human, Mouse
• Product Type: Antibody
• Isotype: IgG