Invitrogen™ HMGB2 Polyclonal Antibody

Rabbit Polyclonal Antibody

Brand:  Invitrogen™ PA5120546

Product Code. 17761944

Description

Positive test controls include: HeLa, 293T, U-87MG, RAW264.7, PC-12. The target is usually found in the following locations: Chromosome, Cytoplasm, Nucleus, Secreted. Immunogen sequence: SAFFLFCSEH RPKIKSEHPG LSIGDTAKKL GEMWSEQSAK DKQPYEQKAA KLKEKYEKDI AAYRAKGKSE AGKKGPGRPT GSKKKNEPED EEEEEEEEDE D.

HMGB2 encodes a member of the non-histone chromosomal high mobility group protein family. The proteins of this family are chromatin-associated and ubiquitously distributed in the nucleus of higher eukaryotic cells. In vitro studies have demonstrated that this protein is able to efficiently bend DNA and form DNA circles. These studies suggest a role in facilitating cooperative interactions between cis-acting proteins by promoting DNA flexibility. This protein was also reported to be involved in the final ligation step in DNA end-joining processes of DNA double-strand breaks repair and V(D)J recombination.

Specifications

• Antigen: HMGB2
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: Hmgb2
• Gene Alias: C80539; high mobility group box 2; high mobility group protein 2; High mobility group protein B2; high-mobility group (nonhistone chromosomal) protein 2; high-mobility group box 2; HMG 2; HMG B2; Hmg2; HMG-2; HMGB2; HMG-B2; HMGB-2
• Host Species: Rabbit
• Purification Method: Affinity Chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 29395, 3148, 97165
• Content And Storage: -20°C, Avoid Freeze/Thaw Cycles
• Form: Liquid

• Applications: ELISA, Western Blot, Immunocytochemistry
• Concentration: 2.66 mg/mL
• Formulation: PBS with 50% glycerol and 0.01% thimerosal; pH 7.3
• Gene Accession No.: P26583, P30681, P52925
• Gene Symbols: Hmgb2
• Immunogen: Synthetic peptide.
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human, Mouse, Rat
• Product Type: Antibody
• Isotype: IgG