Invitrogen™ HMG20A Polyclonal Antibody

Rabbit Polyclonal Antibody

Brand:  Invitrogen™ PA596626

Product Code. 16569461

Description

Immunogen sequence: MENLMTSSTL PPLFADEDGS KESNDLATTG LNHPEVPYSS GATSSTNNPE FVEDLSQGQL LQSESSNAAE GNEQRHEDEQ RSKRGGWSKG RKRKKPLRDS NAPKSPLTGY VRFMNERREQ LRAKRPEVPF PEITRMLGNE WSKLPPEEKQ RYLDEADRDK ERYMKELEQY QKTEAYKVFS RKTQDRQKGK SHRQDAARQA THDHEKETEV KERSVFDIPI FTEEFLNHSK AREAELRQLR KSNMEFEERN AALQKHVESM RTAVEKLEVD VIQERSRNTV LQQHLETLRQ VLTSSFASMP LPGSGETPTV DTIDSYMNRL HSIILANPQD NENFIATVRE VVNRLDR; Positive Samples: Jurkat, 22Rv1, Mouse heart; Cellular Location: Nucleus.

Plays a role in neuronal differentiation as chromatin-associated protein. Acts as inhibitor of HMG20B. Overcomes the repressive effects of the neuronal silencer REST and induces the activation of neuronal-specific genes. Involved in the recruitment of the histone methyltransferase KMT2A/MLL1 and consequent increased methylation of histone H3 lysine 4.

Specifications

• Antigen: HMG20A
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: HMG20A
• Gene Alias: 1200004E06Rik; 5730490E10Rik; FLJ10739; high mobility group 20A; high mobility group protein 20A; HMG box domain containing 1; HMG box-containing protein 20A; HMG domain-containing protein 1; HMG domain-containing protein HMGX1; HMG20A; HMGX1; HMGXB1; Ibraf; Inhibitor of BRAF35; RGD1564760
• Host Species: Rabbit
• Purification Method: Affinity Chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 10363, 66867
• Content And Storage: -20°C, Avoid Freeze/Thaw Cycles
• Form: Liquid

• Applications: ELISA, Western Blot, Immunocytochemistry
• Concentration: 2.32 mg/mL
• Formulation: PBS with 50% glycerol and 0.02% sodium azide; pH 7.3
• Gene Accession No.: Q9DC33, Q9NP66
• Gene Symbols: HMG20A
• Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 1-347 of human HMG20A (NP_0606701).
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human, Mouse
• Product Type: Antibody
• Isotype: IgG