Invitrogen™ HLA-F Polyclonal Antibody

Rabbit Polyclonal Antibody

Brand:  Invitrogen™ PA5100066

Product Code. 16636554

Description

Antibody detects endogenous levels of total HLA-F.

HLA-F belongs to the HLA class I heavy chain paralogues. It is a non-classical heavy chain that forms a heterodimer with a beta-2 microglobulin light chain, with the heavy chain anchored in the membrane. Unlike most other HLA heavy chains, this molecule is localized in the endoplasmic reticulum and Golgi apparatus, with a small amount present at the cell surface in some cell types. It contains a divergent peptide-binding groove, and is thought to bind a restricted subset of peptides for immune presentation. HLA and MHC antibodies play a significant role in Immunopeptidomics, facilitating the identification and characterization of neoantigens through high-performance liquid chromatography coupled to tandem Mass Spectrometry.

Specifications

• Antigen: HLA-F
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: HLA-F
• Gene Alias: CDA12; HLA class I histocompatibility antigen, alpha chain F; HLA class I molecule; HLA F antigen; HLA-5.4; HLA-CDA12; HLAF; HLA-F; Leukocyte antigen F; major histocompatibility complex, class I, F; MHC class I antigen F; MHC class Ib antigen
• Host Species: Rabbit
• Purification Method: Affinity chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 3134
• Content And Storage: -20°C
• Form: Liquid

• Applications: Immunohistochemistry (Paraffin), Western Blot, Immunocytochemistry
• Concentration: 1 mg/mL
• Formulation: PBS with 50% glycerol and 0.02% sodium azide; pH 7.4
• Gene Accession No.: P30511
• Gene Symbols: HLA-F
• Immunogen: A synthesized peptide derived from human HLA-F(Accession P30511), corresponding to amino acid residues R152-R202.
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human, Mouse, Rat
• Product Type: Antibody
• Isotype: IgG