HLA-E Mouse anti-Human, Clone: 3D12HLA-E, Functional Grade, eBioscience™

Mouse Monoclonal Antibody, Functional Grade

Brand:  Affymetrix eBioscience 16-9953-85

Product Code. 15567836

Disclaimers:

For Research Use Only.

Description

The monoclonal antibody 3D12 (HLA-E) recognizes human HLA-E, a member of the Human Leukocyte Antigen family. HLA-E is a MHC Class IB member, which has a specialized role in NK cell recognition. Binding of a restricted set of peptides derived from other Class I leader sequences to the HLA-E and B2M (beta2 microglobulin) complex leads to interaction with NKG2A on NK cells. This binding protects the HLA-G-expressing cell from NK cell killing. HLA-E expression is ubiquitous.

Specifications

• Antigen: HLA-E
• Clone: 3D12HLA-E
• Conjugate: Unlabeled
• Format: Purified
• Isotype: IgG1
• Regulatory Status: RUO
• Primary or Secondary: Primary
• Target Species: Human

• Applications: Functional Assay
• Concentration: 1mg/mL
• Formulation: aqueous buffer, no sodium azide
• Host Species: Murine
• Quantity: 500μg
• Storage Requirements: Store at 2-8°C.
• Monoclonal or Polyclonal: Monoclonal