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HLA-E Mouse anti-Human, Clone: 3D12HLA-E, Functional Grade, eBioscience™

Mouse Monoclonal Antibody, Functional Grade

Brand:  Affymetrix eBioscience 16-9953-85

Code : NEW

Additional Details : Weight : 0.09500kg

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Product Code. 15567836

  • £305.10 / 500µg


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For Research Use Only.


Description

Description

The monoclonal antibody 3D12 (HLA-E) recognizes human HLA-E, a member of the Human Leukocyte Antigen family. HLA-E is a MHC Class IB member, which has a specialized role in NK cell recognition. Binding of a restricted set of peptides derived from other Class I leader sequences to the HLA-E and B2M (beta2 microglobulin) complex leads to interaction with NKG2A on NK cells. This binding protects the HLA-G-expressing cell from NK cell killing. HLA-E expression is ubiquitous.
Specifications

Specifications

HLA-E
3D12HLA-E
Unconjugated
Purified
IgG1
RUO
Primary
Human
Functional Assay
1mg/mL
aqueous buffer, no sodium azide
Murine
500μg
Store at 2-8°C.
Monoclonal
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