HLA-E Mouse anti-Human, Clone: 3D12HLA-E, Functional Grade, eBioscience™

Mouse Monoclonal Antibody, Functional Grade

Overview
Brand: Affymetrix eBioscience

Manufacturer Part Number: 16-9953-85

500UG Anti-Human HLA-E Functional Grade Purified

Code: NEW

Additional Details:
Additional Details: Weight: 0.09500kg



Disclaimers: For Research Use Only.

Product Code. 15567836

Quantity Price
1 £ 305.1 / 500µg
EU Stock 3
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Description and Specification

Specification

Applications Flow Cytometry
Applications Functional Assay
Quantity 500μg
Primary or Secondary Primary
Antigen HLA-E
Format Purified
Formulation aqueous buffer, no sodium azide
Host Species Mouse
Isotype IgG1
Species Reactivity Human
Storage Requirements Store at 2-8°C.
Concentration 1mg/mL
Regulatory Status RUO
Monoclonal or Polyclonal Monoclonal
Clone 3D12HLA-E
Conjugate Unlabeled

The monoclonal antibody 3D12 (HLA-E) recognizes human HLA-E, a member of the Human Leukocyte Antigen family. HLA-E is a MHC Class IB member, which has a specialized role in NK cell recognition. Binding of a restricted set of peptides derived from other Class I leader sequences to the HLA-E and B2M (beta2 microglobulin) complex leads to interaction with NKG2A on NK cells. This binding protects the HLA-G-expressing cell from NK cell killing. HLA-E expression is ubiquitous.